Actively Recruiting
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
Led by Massachusetts General Hospital · Updated on 2025-10-02
60
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
N
National Center for Complementary and Integrative Health (NCCIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression. The main questions it aims to answer in a later fully powered randomized controlled trial are: * Is an adaptation of mindfulness-based cognitive therapy for older Black adults able to improve quality of life? * Will an adapted mindfulness based cognitive therapy reduce pain interference to a greater degree than a traditional health enhancement program?
CONDITIONS
Official Title
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Older adult aged 50 years or older
- Identify with one or more Black racial groups of Africa
- Have muscle, joint, bone, or soft tissue pain lasting more than 3 months with severity over 4 on the NRS
- Mild to moderate depression with PHQ-9 score between 5 and 14
- Fluent and literate in English
- Able and willing to participate in-person and via video
- No changes in antidepressant medication type or dose for at least 6 weeks before screening
- Willing to provide informed consent and follow the study protocol
You will not qualify if you...
- Severe depressive symptoms with PHQ-9 score of 15 or higher
- Current substance abuse or dependence
- Significant cognitive impairment
- More than 8 previous cognitive-behavioral therapy sessions
- Previous mindfulness training or counseling more than once a month
- History or current diagnosis of psychosis
- Active suicidal thoughts or self-harm within the past 90 days
- Currently participating in another behavioral clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
T
Tony V Pham
CONTACT
T
Tony V Pham
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here