Actively Recruiting
Project FIERCE - Mindfulness-Based Meditation to Reduce Stress and Promote Compassion, Joy, and Equanimity in Healthcare Professionals
Led by University of California, Los Angeles · Updated on 2025-12-16
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Healthcare workers often face high levels of stress, depression, and burnout, which can negatively affect their health and patient care. This research aims to evaluate a mindfulness-based intervention inspired by the Buddhist Four Immeasurables practice to reduce perceived stress and improve well-being among 80 full-time healthcare employees. The study also examines effects on depressive symptoms, burnout, sleep quality, psychological well-being, and inflammation, along with underlying factors like compassion and mindfulness. Participants will be randomly assigned to either a six-week online mindfulness program called Building Emotional Strength Training (BEST) or a waitlist control group. The BEST program involves weekly one-hour live group sessions via Zoom focusing on loving-kindness, compassion, joy, and equanimity. Participants are encouraged to practice meditation daily at home, gradually increasing from five to twenty minutes. The control group will receive the intervention after data collection. Throughout the study, participants complete questionnaires and provide blood samples at baseline, mid-course (week 3), and post-intervention (week 6) to assess stress levels and other outcomes. Blood samples are self-collected at home using a simple device. The study measures changes in perceived stress, depression, burnout, sleep, psychological health, and markers of inflammation. Participation lasts about six weeks, with follow-up assessments conducted remotely.
CONDITIONS
Brief Title
A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Full-time physician (M.D. or D.O.)
- At least 18 years of age
- Able to attend the six-week intervention
- Fluent in English
- Access to the internet and email
You will not qualify if you...
- Current regular meditation practice (at least three days per week for five minutes each day)
- Previous participation in a Four Immeasurable course or retreat
- Perceived stress score less than five on the Perceived Stress Scale (PSS-4)
- Regular tobacco use
- Failure to agree to the informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (remote and in-person components)
Duration - Up to 2 weeks before intervention
Participants complete questionnaires and collect a blood sample at home to assess stress and related health measures before the intervention begins.
1 baseline assessment visit (remote and at-home blood collection)
Duration - 6 weeks
Participants attend weekly one-hour live online group meditation classes focused on mindfulness and emotional strength, with guided home practice over six consecutive weeks.
Weekly 1-hour online group sessions for 6 weeks
Duration - 1 day at week 3
Participants complete self-report questionnaires on stress and related variables at the halfway point of the intervention.
1 remote questionnaire completion
Duration - Up to 2 weeks post-intervention
Participants complete questionnaires and collect a second blood sample at home within two weeks after completing the intervention to evaluate outcomes.
1 remote questionnaire completion and 1 at-home blood collection
Trial Site Locations
Total: 1 location
1
University of California, Los Angeles
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
J
J Richard T Korecki, M.A.
J
Julienne E Bower, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here