Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07283744

Project FIERCE - Mindfulness-Based Meditation to Reduce Stress and Promote Compassion, Joy, and Equanimity in Healthcare Professionals

Led by University of California, Los Angeles · Updated on 2025-12-16

80

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Healthcare workers often face high levels of stress, depression, and burnout, which can negatively affect their health and patient care. This research aims to evaluate a mindfulness-based intervention inspired by the Buddhist Four Immeasurables practice to reduce perceived stress and improve well-being among 80 full-time healthcare employees. The study also examines effects on depressive symptoms, burnout, sleep quality, psychological well-being, and inflammation, along with underlying factors like compassion and mindfulness. Participants will be randomly assigned to either a six-week online mindfulness program called Building Emotional Strength Training (BEST) or a waitlist control group. The BEST program involves weekly one-hour live group sessions via Zoom focusing on loving-kindness, compassion, joy, and equanimity. Participants are encouraged to practice meditation daily at home, gradually increasing from five to twenty minutes. The control group will receive the intervention after data collection. Throughout the study, participants complete questionnaires and provide blood samples at baseline, mid-course (week 3), and post-intervention (week 6) to assess stress levels and other outcomes. Blood samples are self-collected at home using a simple device. The study measures changes in perceived stress, depression, burnout, sleep, psychological health, and markers of inflammation. Participation lasts about six weeks, with follow-up assessments conducted remotely.

CONDITIONS

Brief Title

A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Full-time physician (M.D. or D.O.)
  • At least 18 years of age
  • Able to attend the six-week intervention
  • Fluent in English
  • Access to the internet and email
Not Eligible

You will not qualify if you...

  • Current regular meditation practice (at least three days per week for five minutes each day)
  • Previous participation in a Four Immeasurable course or retreat
  • Perceived stress score less than five on the Perceived Stress Scale (PSS-4)
  • Regular tobacco use
  • Failure to agree to the informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (remote and in-person components)

Baseline Assessment

Duration - Up to 2 weeks before intervention

Participants complete questionnaires and collect a blood sample at home to assess stress and related health measures before the intervention begins.

1 baseline assessment visit (remote and at-home blood collection)

Building Emotional Strength Training

Duration - 6 weeks

Participants attend weekly one-hour live online group meditation classes focused on mindfulness and emotional strength, with guided home practice over six consecutive weeks.

Weekly 1-hour online group sessions for 6 weeks

Mid-Course Assessment

Duration - 1 day at week 3

Participants complete self-report questionnaires on stress and related variables at the halfway point of the intervention.

1 remote questionnaire completion

Post-Intervention Assessment

Duration - Up to 2 weeks post-intervention

Participants complete questionnaires and collect a second blood sample at home within two weeks after completing the intervention to evaluate outcomes.

1 remote questionnaire completion and 1 at-home blood collection

Trial Site Locations

Total: 1 location

1

University of California, Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

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Research Team

J

J Richard T Korecki, M.A.

J

Julienne E Bower, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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