Actively Recruiting
Mindfulness in Chronic Kidney Disease
Led by Emory University · Updated on 2025-10-21
150
Participants Needed
1
Research Sites
362 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
N
National Center for Complementary and Integrative Health (NCCIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will test whether mindfulness meditation (MM) improves sympathetic function in chronic kidney disease (CKD) and whether transcutaneous vagus nerve stimulation (tVNS) optimizes the sympatho-inhibitory effects of mindfulness meditation (MM) and restores autonomic balance in CKD patients.
CONDITIONS
Official Title
Mindfulness in Chronic Kidney Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Stage III or IV chronic kidney disease as defined by the CKD-EPI creatinine equation
- Stable kidney function with no more than 1 cc/min/1.73 m2 decline in eGFR per month over the past 3 months
You will not qualify if you...
- Severe chronic kidney disease with eGFR less than 15 cc/min
- Diabetic neuropathy
- Autonomic dysfunction
- Any serious disease affecting survival
- Anemia with hemoglobin less than 10 g/dL
- Treatment with central alpha-agonists or monoamine oxidase inhibitors
- Heart attack or stroke within the past 6 months
- Uncontrolled high blood pressure (BP ≥ 170/100 mm Hg)
- Low blood pressure (BP less than 100/50 mm Hg)
- Slow heart rate (less than 55 beats per minute)
- Ongoing drug or alcohol abuse (more than 2 drinks/day for men, more than 1 drink/day for women)
- Surgery within the past 3 months
- Recent changes in blood pressure medications within the past month
- Pregnancy or plans to become pregnant
- Psychosis or suicidal thoughts
- Implanted electronic or metal devices like pacemakers
- Implanted hearing aids, bone plates, carotid stents, or screws near the neck
- Carotid artery disease
- Use of other stimulating devices such as TENS units
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Atlanta VA Medical Center
Atlanta, Georgia, United States, 30322
Actively Recruiting
Research Team
J
Jeanie Park, MD
CONTACT
D
Dana DaCosta
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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