Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT06972303

Mindfulness Meditation for Insomnia

Led by Brigham and Women's Hospital · Updated on 2026-02-25

30

Participants Needed

1

Research Sites

151 weeks

Total Duration

On this page

Sponsors

B

Brigham and Women's Hospital

Lead Sponsor

N

National Center for Complementary and Integrative Health (NCCIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators will conduct a 3-arm, pilot RCT where participants (N=30) will be randomized in a 1:1:1 design to 4 weeks of instructed bedtime MM practice at night (n=10) vs. uninstructed MM (n=10) vs. sleep hygiene education only (n=10). Aim 1 is to understand the feasibility and acceptability of the intervention and study procedures. Aim 2 is to explore patterns of within-group changes in sleep outcomes (i.e., insomnia severity and sleep quality). Patient-reported outcomes will be collected using a HIPAA-compliant electronic data management system (REDCap). Following informed consent, participants will receive links to REDCap surveys via email at Weeks 0, 4, 8, and 16. The investigators will also conduct a post-intervention interview at the end of Week 4 and an exit interview at Week 16. All participants will also receive a research kit with wearable devices and meet with our staff after they receive the kit for instructions. Data collected in the pilot RCT will help us to preliminarily identify tools for subjective measures and physiological signals to inform a future trial.

CONDITIONS

Official Title

Mindfulness Meditation for Insomnia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years and older
  • Chronic insomnia occurring 3 or more nights per week for at least 3 months, defined by DSM-V or ICSD-3
  • Main complaint of difficulty falling asleep with sleep onset latency greater than 20 minutes
  • Insomnia Severity Index score of 15 or higher
  • Ability to speak and understand English
  • Access to a smartphone or tablet capable of installing the mobile app
Not Eligible

You will not qualify if you...

  • Current diagnosis of sleep disorders other than insomnia (e.g., narcolepsy, restless leg syndrome, REM sleep behavior disorder)
  • Shift work or routine night shift work
  • Pregnancy or breastfeeding for women
  • Regular practice (twice a week or more) of mind-body interventions
  • Use of pacemaker or cardiovascular medications affecting heart rate (e.g., beta-blockers)
  • Neurological disorders such as epilepsy, dementia, stroke, Parkinson's disease, neuroinfections, brain tumors
  • Current diagnosis of psychotic, substance use, or trauma-related disorders
  • Use of medications that affect sleep such as anxiolytics, benzodiazepines, selective serotonin reuptake inhibitors, hypnotics
  • Hearing impairment or hearing loss
  • Must report any medication use for at least 2 weeks before and during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

Y

Yan Ma

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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