Actively Recruiting

Age: 18Years - 99Years
All Genders
ID04524416

A Prospective, Open, Multicentre Study Analysing the Long-term Safety of MINIject Glaucoma Implants in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive Medications

Led by iSTAR Medical · Updated on 2025-02-28

300

Participants Needed

9

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the long-term safety and performance of the MINIject glaucoma implant in patients with open-angle glaucoma or ocular hypertension not controlled by topical hypotensive medications. This observational study includes patients who previously received the MINIject implant in an earlier clinical trial and aims to follow them for up to five years after implantation to monitor outcomes. The study involves annual follow-up visits from two to five years post-implantation. During these visits, standard eye examinations will be performed, including measuring intraocular pressure, examining the fundus, ocular imaging, and checking for any eye-related adverse events. The implant was placed in a prior study and is not part of the current study procedures. Participants will undergo regular ophthalmologic assessments to track the implant's safety and performance over time. The primary outcome measured is the proportion of patients experiencing serious device-related adverse events in the treated eye five years after implantation. Participants will provide informed consent and attend visits as scheduled to support comprehensive long-term monitoring.

CONDITIONS

Brief Title

MINIject Global Long-Term Follow-up Study

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient who received a MINIject glaucoma implant within a prior clinical study
  • Patient continues to have MINIject implanted at the point of enrolment
  • Patient must provide written informed consent to participate
Not Eligible

You will not qualify if you...

  • Individuals under tutorship or trusteeship
  • Patient who is unwilling to return to the study visits and undergo study assessments, as required by clinical study protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 3 years

Participants are followed for long-term safety and performance assessments of the MINIject glaucoma implant, including ophthalmologic examinations and ocular imaging.

Annual visits for up to 3 years

Trial Site Locations

Total: 9 locations

1

Clinica Oftalmologica del Caribe

Barranquilla, Colombia

Actively Recruiting

2

Center Hospotalier Universitaire Genoble Alpes

Grenoble, France, 38043

Active, Not Recruiting

3

Hopital de la Croix-Rousse

Lyon, France, 69417

Active, Not Recruiting

4

Uniklinik Köln

Cologne, North Rhine-Westphalia, Germany, 50937

Active, Not Recruiting

5

Universitätsklinikum Mainz

Mainz, Rhineland-Palatinate, Germany, 55131

Active, Not Recruiting

6

Klinikum der Universität München

München, Germany, 81377

Actively Recruiting

7

Maxivision Eye Hospital

Hyderabad, Telangana, India, 500034

Actively Recruiting

8

Panama Eye Center

Panama City, Panama

Active, Not Recruiting

9

Hospital Clínico San Carlos

Madrid, Spain

Active, Not Recruiting

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Research Team

E

Esma Islamaj, PhD

P

Pascale Ducloux

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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