Actively Recruiting

Age: 18Years +
All Genders
NCT04739072

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

Led by M.D. Anderson Cancer Center · Updated on 2025-11-13

1000

Participants Needed

10

Research Sites

318 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study investigates if circulating tumor DNA (ctDNA) and other tumor-related molecules/chemicals released in the blood can help doctors predict if colorectal cancer may come back or spread. Tumors shed DNA and other cancer related chemicals into the blood that can be identified and studied further to provide information about the cancer. Information gathered from this study may help researchers better understand if ctDNA found in the blood can predict whether colorectal cancer may come back or spread.

CONDITIONS

Official Title

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Histological or cytological confirmation of colorectal adenocarcinoma
  • Patients with any stage of colorectal adenocarcinoma eligible for curative intent treatment
  • Patients with stage II-IV colorectal cancer post-R0 resection enrolled before or up to 3 months after surgery and before starting adjuvant therapy
  • Ability to understand and willing to sign informed consent
  • Willingness to undergo standard surveillance after completing curative therapies
  • Willingness to provide blood samples for research
Not Eligible

You will not qualify if you...

  • Presence of active cancers other than colorectal adenocarcinoma that could interfere with plasma marker detection or interpretation
  • Severe systemic illnesses or concurrent diseases that would make participation inappropriate according to the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 10 locations

1

Banner - MD Anderson Cancer Center

Gilbert, Arizona, United States, 85234

Terminated

2

Baptist- MD Anderson Cancer Center

Jacksonville, Florida, United States, 32207

Terminated

3

The Queen's Medical Center

Honolulu, Hawaii, United States, 96813

Terminated

4

St. Luke's Cancer Institute

Boise, Idaho, United States, 83712

Terminated

5

Cooper Hospital UNIV MED CTR.

Camden, New Jersey, United States, 08103

Terminated

6

UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, United States, 75390

Terminated

7

Houston Methodist Cancer Center

Houston, Texas, United States, 77030

Terminated

8

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

9

UT Health San Antonio MD Anderson Cancer Center

San Antonio, Texas, United States, 78229

Terminated

10

Baylor Scott & White Research Institute

Temple, Texas, United States, 76508

Terminated

Loading map...

Research Team

A

Arvind Dasari

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here