Actively Recruiting
Multicenter International Prospective Analysis on Minimally Invasive Treatments of the Thyroid for Micropapillary Thyroid Carcinoma
Led by European Institute of Oncology · Updated on 2024-03-27
270
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating Minimally Invasive Treatments of the Thyroid (MITT) as a possible alternative to surgery for patients with Papillary Thyroid MicroCarcinoma (PTMC). This observational study aims to establish a prospective registry of patients treated with MITT to validate the safety of the procedure and collect long-term results in a large group of patients. The study is led by the European Institute of Oncology. The study involves image-guided thermal ablation, a procedure that delivers precise heat to the tumor while sparing surrounding thyroid tissue. This minimally invasive treatment is being studied because it may have similar effectiveness to surgery but with fewer complications, better quality of life, and improved cosmetic outcomes. Patients diagnosed with micropapillary thyroid carcinoma will undergo this treatment and be followed over time. Participants will be monitored for safety, including recording any major complications within one month after treatment. Long-term follow-up will track the occurrence of local recurrence, distant metastasis, and mortality over 10 years. Patients must be accessible for follow-up visits, and data will be collected to assess the procedure's outcomes. The total participation duration spans at least 10 years for long-term monitoring.
CONDITIONS
Brief Title
Minimally Invasive Treatments of the Thyroid
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years or older
- Diagnosis of papillary thyroid microcarcinoma confirmed by cytology
- Suitable for minimally invasive treatments of the thyroid (MITT)
- Written informed consent signed and dated prior to inclusion
- Accessibility for follow-up visits
You will not qualify if you...
- Tumors larger than 1 cm
- Non-papillary cytological types
- Refusal of minimally invasive thyroid treatments (MITT)
- Unsuitability for MITT
- Unmanageable coagulation disorders
- Psychiatric, addictive, or other disorders compromising ability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo image-guided thermal ablation as a minimally invasive treatment for micropapillary thyroid carcinoma.
1 treatment visit (in-person)
Duration - Up to 10 years
Participants are monitored for safety and long-term outcomes including local recurrence, distant metastasis, and survival after treatment.
Regular follow-up visits over 10 years
Trial Site Locations
Total: 1 location
1
European Institute of Oncology
Milan, Italy
Actively Recruiting
Research Team
G
Giovanni Mauri
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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