Actively Recruiting
MINImising Total Radiation EXposure in Preterm Infants
Led by Western Health, Australia · Updated on 2026-04-16
180
Participants Needed
1
Research Sites
189 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Being born too early (preterm birth) is the leading cause of death in children world-wide. In Australia, 97% of very preterm babies who are admitted to Neonatal Intensive Care Units need breathing support after birth to survive. Despite this significant global impact, neonatal clinicians have few tools available to guide breathing support. Currently, the only lung imaging tool that is routinely used in the Neonatal Intensive Care Unit is a chest X-ray. To reduce radiation exposure, chest X-rays are usually only performed one or two times a day. As chronic lung disease in babies who survive preterm birth is increasing, there is an urgent need to develop new ways to monitor the lungs of these fragile babies. Lung ultrasound is a form of imaging that is fast, gentle and radiation free. However, it has not been routinely adopted into caring for preterm babies in most countries. This is because there are no randomised controlled trials that have demonstrated the benefit and safety of using lung ultrasound as the first-line imaging tool in preterm babies. The investigators will conduct a randomised controlled trial to demonstrate that lung ultrasound is a quick, safe and accurate alternative to chest x-rays in preterm babies.
CONDITIONS
Official Title
MINImising Total Radiation EXposure in Preterm Infants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infant born from 22 to 31 weeks and 6 days gestation
- Infant admitted to Neonatal Intensive Care Unit
- Infant requires lung imaging for respiratory issues
- Parent or guardian can provide informed consent
You will not qualify if you...
- Chest X-ray only needed to confirm device positions (e.g., central line, endotracheal tube)
- Chest X-ray only needed for non-respiratory reasons (e.g., heart assessment)
- Clinician concerned about baby's stability for ultrasound
- Baby's skin cannot tolerate ultrasound gel
- Parent or guardian refuses or cannot provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Joan Kirner Women's and Children's, Sunshine Hospital, Western Health
Melbourne, Victoria, Australia, 3021
Actively Recruiting
Research Team
A
Arun Sett, PhD
CONTACT
N
Niranjan Abraham, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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