Exploring the Lowest Power and Frequency of Repeated Low-level Red-light to Control Myopia in Children Aged 8 to 10 Years

What this Trial Is About

Researchers are investigating the minimum power and frequency of Repeated Low-level Red-light RLRL therapy needed to control myopia progression in children aged 8 to 10 years with low myopia. The study also examines the rebound effect on myopia progression after stopping RLRL treatment with different combinations of power and frequency. This prospective, double-blind, randomized controlled trial aims to provide clearer evidence on how RLRL exposure can best prevent worsening of myopia, a condition linked to serious eye complications. Participants will use a low-intensity red light device alongside their regular single vision spectacle lenses. The treatment is given Monday to Friday with sessions lasting 3 minutes, spaced by at least 4 hours. Various groups will receive different power levels and frequencies of red light, ranging from 0.3 mW to 2.0 mW once or twice daily, while a control group will receive a sham red LED treatment twice daily. This setup helps assess how changes in treatment dose affect myopia control. Throughout the study, childrens eye measurements will be closely monitored at multiple time points including 1 week, 1, 2, 3, and 4 months. Assessments include axial length and refractive error measurements, visual acuity, choroidal thickness, and retinal function tests. Researchers will also track any side effects such as glare or afterimages. The primary outcome is the percentage of participants with minimal axial length increase after 3 months of treatment, with additional follow-up after treatment stops to observe any rebound effects.

Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression