Actively Recruiting
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2024-10-24
2130
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a new 10-minute cardiovascular magnetic resonance (CMR) imaging protocol designed to improve current CMR procedures for patients with various heart conditions, including coronary artery disease, cardiomyopathies, and other cardiac diseases. The study aims to develop a standardized, contrast-free imaging method that can be applied to about 70% of cardiac patients. The goal is to assess whether this shorter protocol enhances diagnostic decision-making and reduces healthcare costs. The study involves two groups: healthy volunteers over 18 years old without significant cardiovascular or respiratory conditions, and patients over 18 years who require a clinically indicated CMR exam. The new protocol focuses on heart function and tissue characterization without using contrast agents. Researchers will compare the new 10-minute protocol to standard CMR imaging, evaluating its clinical feasibility, performance, and cost-effectiveness in different patient populations. Participants will undergo CMR scans using both the new and standard protocols. Researchers will monitor diagnostic results, scan completion rates, scan sequence times, adverse events, and cost differences between methods. Various heart tissue measurements and reproducibility between different readers and scanners will also be assessed. The study spans from 2019 to 2025, with ongoing safety monitoring during imaging sequences and a focus on improving the efficiency and quality of cardiac imaging.
CONDITIONS
Brief Title
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Able to give informed consent
- For healthy volunteers: no significant medical conditions affecting cardiovascular or respiratory systems
- For patients: clinically indicated cardiovascular magnetic resonance exam
You will not qualify if you...
- Presence of MRI-incompatible devices such as pacemakers, defibrillators, or implanted foreign bodies
- Consumption of caffeinated drinks or foods (including cocoa and chocolate) within 12 hours before the exam
- Regular nicotine use during the last 6 months
- Use of vasoactive medications (e.g., nitroglycerin) within 12 hours before the exam (patients only)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single day
Participants undergo a 10-minute cardiovascular magnetic resonance protocol without contrast injection to assess cardiac function and tissue characterization.
1 visit (in-person)
Duration - Up to 6 years
Participants are observed over time to compare diagnostic results and monitor for any adverse events related to the cardiovascular magnetic resonance sequences.
Follow-up visits as needed
Trial Site Locations
Total: 1 location
1
McGill University Health Center
Montreal, Quebec, Canada, H4A 3J1
Actively Recruiting
Research Team
E
Elizabeth Konidis
A
Adonis Rodaros
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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