Actively Recruiting

Age: 18Years +
All Genders
NCT04494295

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

Led by Integra LifeSciences Corporation · Updated on 2026-02-06

500

Participants Needed

20

Research Sites

468 weeks

Total Duration

On this page

Sponsors

I

Integra LifeSciences Corporation

Lead Sponsor

I

Icahn School of Medicine at Mount Sinai

Collaborating Sponsor

AI-Summary

What this Trial Is About

This registry will study the use of the Aurora® Surgiscope to provide surgical access and visualization in minimally invasive removal of hematoma in the brain. Many methods of hematoma removal are available and will be based on surgeon preference. The impact of patient selection and time to surgery from last known well time will be explored.

CONDITIONS

Official Title

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Acute, spontaneous, primary supratentorial intracerebral hemorrhage larger than 20 mL confirmed by head CT
  • Surgery can start within 24 hours of last known well time or symptom awakening
  • NIH Stroke Scale score greater than 5
  • Baseline Modified Rankin Scale score 2 or less
  • CT Angiography shows no vascular malformation
Not Eligible

You will not qualify if you...

  • Presence of underlying vascular lesion causing the hemorrhage
  • Severe neurological deficit such as fixed or dilated pupils or bilateral extensor posturing
  • Hemorrhage located in the infratentorial or brainstem area
  • Known life expectancy less than 6 months
  • Uncorrectable bleeding disorder
  • Presence of mechanical heart valve
  • Pregnancy
  • Participation in another interventional clinical trial
  • Inability to meet study follow-up requirements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 20 locations

1

Providence Health

Burbank, California, United States, 91505

Actively Recruiting

2

University of Miami

Miami, Florida, United States, 33136

Actively Recruiting

3

University of South Florida

Tampa, Florida, United States, 33606

Actively Recruiting

4

Rush University Medical Center

Chicago, Illinois, United States, 60612

Actively Recruiting

5

MedStar Health Research Institute

Baltimore, Maryland, United States, 21237

Not Yet Recruiting

6

Corewell Health

Grand Rapids, Michigan, United States, 49503

Terminated

7

University of Missouri

Columbia, Missouri, United States, 65201

Actively Recruiting

8

Washington University in St. Louis

St Louis, Missouri, United States, 63110

Actively Recruiting

9

JFK university

Edison, New Jersey, United States, 08820

Actively Recruiting

10

University at Buffalo

Buffalo, New York, United States, 14260

Actively Recruiting

11

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029

Actively Recruiting

12

University of North Carolina

Chapel Hill, North Carolina, United States, 27599-1350

Actively Recruiting

13

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Actively Recruiting

14

University of Oklahoma

Oklahoma City, Oklahoma, United States, 73104

Actively Recruiting

15

Pennsylvania State University

Hershey, Pennsylvania, United States, 17033

Actively Recruiting

16

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Terminated

17

Prisma Health - Upstate

Greenville, South Carolina, United States, 29601

Actively Recruiting

18

UT Health

Houston, Texas, United States, 77030

Not Yet Recruiting

19

University of Utah

Salt Lake City, Utah, United States, 84112

Actively Recruiting

20

University of Washington - Harborview

Seattle, Washington, United States, 98104

Actively Recruiting

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Research Team

H

Habib Nacer-Chérif

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation | DecenTrialz