Actively Recruiting

Phase Not Applicable
Age: 20Years - 80Years
All Genders
ID05467813

Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation: A Cross-Setting Study

Led by National Taiwan University Hospital · Updated on 2025-06-18

50

Participants Needed

5

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are exploring innovative treatment strategies for stroke rehabilitation, focusing on hybrid interventions that combine mirror therapy followed by augmented reality. Stroke often causes long-term disability and a significant health and financial burden. This study aims to examine new rehabilitation regimens including bilateral and unilateral mirror therapy combined with augmented reality exergaming, which provides real-time feedback to encourage active participation. The study also compares how these therapies work in clinic versus home settings, using telehealth techniques to monitor home practice. Participants will be divided into groups receiving different sequences of clinic-based and home-based rehabilitation. The experimental group starts with clinic-based therapy followed by home-based therapy after a 3-week washout period. Another group begins with home-based therapy then switches to clinic-based therapy, while a control group receives clinic-based therapy throughout but practices at home regularly. Mirror therapy involves movements with the affected and unaffected arms using a mirror, and augmented reality exercises include balance, daily activities, and cognitive training with safety supports. During the study, participants will be assessed at baseline, 3, 6, 9, and 21 weeks using measures like the Fugl-Meyer Assessment and Berg Balance Scale to evaluate motor and sensory function, mobility, daily function, and quality of life. Additional evaluations include cognitive assessments, adherence to home exercises, and monitoring for adverse responses. Telehealth support helps track home therapy, and the total study duration for each participant averages 21 weeks, ensuring thorough monitoring and data collection.

CONDITIONS

Brief Title

Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation

Who Can Participate

Age: 20Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have had a first-ever unilateral stroke at least 3 months ago
  • Are between 20 and 80 years old
  • Have a baseline upper extremity Fugl-Meyer Assessment score greater than 10
  • Do not have severe spasticity in any joints of the affected arm (Modified Ashworth Scale less than 3)
  • Can follow instructions from evaluators and therapists (Mini-Mental State Examination score of 22 or higher)
  • Can stand in a step-standing position for at least 30 seconds
  • Can walk at least 10 meters with or without a walking device
  • Do not have severe vision impairments or other major neurological diseases
  • Are able to participate in a 9-week rehabilitation program
  • Are not participating in other studies during this study period and willing to provide informed written consent
Not Eligible

You will not qualify if you...

  • Have acute inflammation
  • Have serious medical problems or poor physical conditions that could be harmful for study participation

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 9 weeks

Participants receive rehabilitation involving mirror therapy preceding augmented reality exercises or conventional therapy. This includes clinic-based and home-based sessions with telehealth monitoring, focusing on motor, balance, daily function, and cognitive tasks.

Multiple visits in clinic and monitored home sessions over 9 weeks

Follow-up

Duration - Up to 12 weeks after treatment ends

Participants are monitored after treatment completion to assess lasting effects and safety.

Visits at 3, 6, 9, and 21 weeks from baseline assessments

Trial Site Locations

Total: 5 locations

1

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Foundation

New Taipei City, Taiwan

Actively Recruiting

2

Feng Yuan Hospital, Ministry of Health and Welfare

Taichung, Taiwan

Actively Recruiting

3

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

4

Taipei Hospital, Ministry of Health and Welfare

Taipei, Taiwan

Actively Recruiting

5

Linkou Chang Gung Memorial Hospital, Chang Gung Medical Foundation

Taoyuan, Taiwan

Actively Recruiting

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Research Team

K

Keh-Chung Lin, Sc.D

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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