Study of Mirror Therapy and Augmented Reality for Stroke Rehabilitation in Clinic and Home Settings
Led by National Taiwan University Hospital · Updated on 2025-06-18
50
Participants Needed
5
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are exploring innovative treatment strategies for stroke rehabilitation, focusing on hybrid interventions that combine mirror therapy followed by augmented reality. Stroke often causes long-term disability and a significant health and financial burden. This study aims to examine new rehabilitation regimens including bilateral and unilateral mirror therapy combined with augmented reality exergaming, which provides real-time feedback to encourage active participation. The study also compares how these therapies work in clinic versus home settings, using telehealth techniques to monitor home practice.
Participants will be divided into groups receiving different sequences of clinic-based and home-based rehabilitation. The experimental group starts with clinic-based therapy followed by home-based therapy after a 3-week washout period. Another group begins with home-based therapy then switches to clinic-based therapy, while a control group receives clinic-based therapy throughout but practices at home regularly. Mirror therapy involves movements with the affected and unaffected arms using a mirror, and augmented reality exercises include balance, daily activities, and cognitive training with safety supports.
During the study, participants will be assessed at baseline, 3, 6, 9, and 21 weeks using measures like the Fugl-Meyer Assessment and Berg Balance Scale to evaluate motor and sensory function, mobility, daily function, and quality of life. Additional evaluations include cognitive assessments, adherence to home exercises, and monitoring for adverse responses. Telehealth support helps track home therapy, and the total study duration for each participant averages 21 weeks, ensuring thorough monitoring and data collection.
CONDITIONS
Brief Title
Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation
Research Team
K
Keh-Chung Lin, Sc.D
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Have had a first-ever unilateral stroke at least 3 months ago
Are between 20 and 80 years old
Have a baseline upper extremity Fugl-Meyer Assessment score greater than 10
Do not have severe spasticity in any joints of the affected arm (Modified Ashworth Scale less than 3)
Can follow instructions from evaluators and therapists (Mini-Mental State Examination score of 22 or higher)
Can stand in a step-standing position for at least 30 seconds
Can walk at least 10 meters with or without a walking device
Do not have severe vision impairments or other major neurological diseases
Are able to participate in a 9-week rehabilitation program
Are not participating in other studies during this study period and willing to provide informed written consent
You will not qualify if you...
Have acute inflammation
Have serious medical problems or poor physical conditions that could be harmful for study participation
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 9 weeks
Participants receive rehabilitation involving mirror therapy preceding augmented reality exercises or conventional therapy. This includes clinic-based and home-based sessions with telehealth monitoring, focusing on motor, balance, daily function, and cognitive tasks.
Multiple visits in clinic and monitored home sessions over 9 weeks
Follow-up
Duration - Up to 12 weeks after treatment ends
Participants are monitored after treatment completion to assess lasting effects and safety.
Visits at 3, 6, 9, and 21 weeks from baseline assessments
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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Published Research Related To This Trial
Construct validity, responsiveness, minimal detectable change, and minimal clinically important difference of the stroke self-efficacy questionnaire in individuals receiving stroke rehabilitation.