Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
All Genders
NCT04119544

Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)

Led by Clinique Les Trois Soleils · Updated on 2026-03-18

66

Participants Needed

5

Research Sites

450 weeks

Total Duration

On this page

Sponsors

C

Clinique Les Trois Soleils

Lead Sponsor

C

Clinalliance Villiers-sur-Orge

Collaborating Sponsor

AI-Summary

What this Trial Is About

Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb. The use of mirror therapy allows the activation of the mirror neurons involved to stimulate brain plasticity after brain damage.The IVS (Intensive Visual Stimulation) device allows an easy implementation of mirror therapy by filming the valid upper limb and projecting the inverted image onto a screen placed above the parietal arm thus producing the illusion of movement of the parietal arm. The main hypothesis of this study is that the structured practice of a large number of upper limb targeted movement repetitions using an intensive visual numerical simulation device as a partial replacement for routine care (conventional occupational therapy) in the sub-acute phase of stroke will increase the active function (motor function and functional abilities) of the distal end of the upper limb compared to conventional rehabilitation. Objectives: This randomized controlled trial will evaluate the effects of partial substitution of routine care (occupational therapy) by structured movement repetition programs by Intensive Visual Simulation using an IVS3 device, on the distal motor control of the upper hemiparesis limb, between 4 and 10 weeks after the stroke, compared to a program with conventional care alone.

CONDITIONS

Official Title

Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Stroke hemiparesis from a unilateral focal lesion dated 4 to 10 weeks before baseline
  • Fugl-Meyer wrist and hand total sub-scores less than 16
  • Patient agrees to sign an informed consent
  • Patient is affiliated with French Social Security
Not Eligible

You will not qualify if you...

  • Cognitive dysfunction or progressive illness preventing effective communication or participation
  • Phasic disorders preventing understanding of instructions
  • Participation in another clinical trial
  • Neurological conditions before the stroke
  • Prior mirror therapy or IVS rehabilitation before inclusion
  • Rheumatological disease of the hand and wrist
  • Person under legal protection measures

AI-Screening

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Trial Site Locations

Total: 5 locations

1

CHU Sébastopol

Reims, Champagne-Ardenne, France, 51092

Not Yet Recruiting

2

Clinique Napoléon

Saint-Paul-lès-Dax, New Aquitaine, France, 40990

Not Yet Recruiting

3

Clinique Les Trois Soleils

Boissise-le-Roi, France, 77310

Actively Recruiting

4

CRF Pasori

Cosne-Cours-sur-Loire, France, 58200

Actively Recruiting

5

Clinalliance Villiers-sur Orge

Villiers-sur-Orge, France, 91700

Actively Recruiting

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Research Team

S

SAS Les POMPON

CONTACT

C

Christophe DURET, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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