Actively Recruiting
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
Led by CooperVision, Inc. · Updated on 2025-08-17
900
Participants Needed
30
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
CONDITIONS
Official Title
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Informed Consent and Assent have been completed
- Be between 8 and 12 years of age inclusive at the time of enrollment
- Spherical Equivalent Refractive Error between -0.75 D and -4.00 D at baseline in each eye
- Best-corrected visual acuity of +0.10 logMAR (20/25 Snellen equivalent) or better in each eye
- Anisometropia of 1.50 D SERE or less
- Astigmatism of 0.75 D or less
- Free of ocular disease or abnormalities including any corneal scar
- Currently have good general health
- Agree to accept the lens assigned by randomization
- Able to understand the study and willing to follow study instructions
- Able to comply with study procedures including visual acuity and eye measurements
- Able to maintain the visit schedule
- Willing to participate in the trial for 4 years
- Interested in wearing contact lenses approximately 10 hours per day, 6 days per week
- Possesses or will obtain wearable and visually functional eyeglasses (20/40 or better)
You will not qualify if you...
- Current or prior use of any myopia control methods such as bifocals, progressive addition lenses, orthokeratology, atropine, or pirenzepine
- Use of any medications or artificial tears that interfere with contact lens wear or eye measurements
- Previously worn or currently wearing rigid gas permeable contact lenses including orthokeratology lenses
- Any acute or subacute inflammation or infection of the anterior eye chamber
- Any eye disease, injury, or abnormality affecting the cornea, conjunctiva, or eyelids
- Severe dry eyes
- Corneal hypoesthesia unless aphakic
- Any systemic disease affecting the eye or worsened by contact lenses
- Allergic reactions to contact lenses or solutions
- Any active corneal infection
- Eyes that are red or irritated
- Inability to follow lens handling or wear regimen
- History of corneal ulcers, infiltrates, viral or fungal infections, or recurrent ocular infections
- Giant papillary conjunctivitis
- Known allergy to fluorescein, benoxinate, proparacaine, or tropicamide
- Keratoconus or irregular cornea
- Strabismus or amblyopia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 30 locations
1
University of Alabama School of Optometry
Birmingham, Alabama, United States, 35233
Actively Recruiting
2
Marshall B. Ketchum University Southern California College of Optometry
Fullerton, California, United States, 92831
Actively Recruiting
3
Vision Solutions Optometry Inc
La Mesa, California, United States, 91942
Actively Recruiting
4
Paje Optometric
Santa Ana, California, United States, 92704
Actively Recruiting
5
Coan Eye Care and Optical Boutique
Ocoee, Florida, United States, 34761
Actively Recruiting
6
West Broward Eyecare Associates
Tamarac, Florida, United States, 33321
Actively Recruiting
7
Bright Eyes Family Vision Care
Tampa, Florida, United States, 33626
Actively Recruiting
8
SoLo Eye Care & Eyewear Gallery
Chicago, Illinois, United States, 60608
Actively Recruiting
9
Illinois College of Optometry
Chicago, Illinois, United States, 60616
Actively Recruiting
10
Chicago College of Optometry
Downers Grove, Illinois, United States, 60515
Actively Recruiting
11
Carillon Vision Care
Glenview, Illinois, United States, 60025
Actively Recruiting
12
Brain Vision Institute
Schaumburg, Illinois, United States, 60194
Actively Recruiting
13
Clinical Optics Research Lab at IU School of Optometry
Bloomington, Indiana, United States, 47406
Actively Recruiting
14
Kannarr Eye Care
Pittsburg, Kansas, United States, 66762
Actively Recruiting
15
New England College of Optometry
Boston, Massachusetts, United States, 02115
Actively Recruiting
16
Cornea and Contact Lens Institute
Edina, Minnesota, United States, 55436
Actively Recruiting
17
Vision Source EyeCare
Kansas City, Missouri, United States, 64111
Actively Recruiting
18
Athens Eye Care
Athens, Ohio, United States, 45701
Actively Recruiting
19
Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
20
ProCare Vision Center, Inc.
Granville, Ohio, United States, 43023
Actively Recruiting
21
Miamisburg Vision Care
Miamisburg, Ohio, United States, 45342
Actively Recruiting
22
Eye Care Professionals
Powell, Ohio, United States, 43065
Actively Recruiting
23
Southern College of Optometry
Memphis, Tennessee, United States, 38104
Actively Recruiting
24
Texas State Optical
Beaumont, Texas, United States, 77706
Actively Recruiting
25
University of Houston College of Optometry
Houston, Texas, United States, 77204
Actively Recruiting
26
Vision One Eyecare
Katy, Texas, United States, 77450
Actively Recruiting
27
Lone Star Vision
Plano, Texas, United States, 75024
Actively Recruiting
28
Utah Eye Centers
Ogden, Utah, United States, 84403
Actively Recruiting
29
Virginia Pediatric Eye Care
Chesapeake, Virginia, United States, 23320
Actively Recruiting
30
Factoria Eye Clinic
Bellevue, Washington, United States, 98006
Actively Recruiting
Research Team
K
Kathryn Richdale, OD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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