Actively Recruiting

Phase Not Applicable
All Genders
Healthy Volunteers
NCT07328815

Mitigating Automation Bias in Physician-LLM Diagnostic Reasoning Using Behavioral Nudges

Led by Lahore University of Management Sciences · Updated on 2026-03-31

50

Participants Needed

1

Research Sites

28 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this randomized controlled trial is to evaluate whether behavioral nudges can reduce automation bias, the uncritical acceptance of automated output, in physicians using large language models (LLM) like ChatGPT-5.1 for clinical decision-making. The main question it aims to answer is: Does a dual-mechanism behavioral nudge intervention (baseline accuracy anchoring plus case-specific color-coded confidence signals) reduce physicians' uncritical acceptance of incorrect LLM recommendations? Researchers will compare physicians who receive LLM recommendations along with a behavioral nudge to those who receive LLM recommendations without the nudge to assess if the nudge reduces automation bias. Participants will: * Evaluate six clinical vignettes accompanied by LLM-generated recommendations (half containing deliberate, clinically significant errors). * Control group: Be able to view LLM recommendations in standard format without the nudge. * Treatment group: Be able to view ChatGPT's diagnostic accuracy on standard medical datasets as an initial anchor, then receive color-coded confidence signals alongside each recommendation (e.g., red for low confidence). * Have their responses evaluated by blinded reviewers using an expert-developed assessment rubric to detect uncritical acceptance of erroneous information.

CONDITIONS

Official Title

Mitigating Automation Bias in Physician-LLM Diagnostic Reasoning Using Behavioral Nudges

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be a full or provisionally registered medical practitioner with the Pakistan Medical and Dental Council (PMDC)
  • Have completed the Bachelor of Medicine, Bachelor of Surgery (MBBS) degree or its equivalent
  • Have completed at least 10 hours of structured training on ChatGPT or a similar large language model, including hands-on practice in prompt engineering and content evaluation
Not Eligible

You will not qualify if you...

  • Be a registered medical practitioner with PMDC in other fields such as Bachelor of Dental Surgery (BDS)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Lahore University of Management Sciences

Lahore, Punjab Province, Pakistan, 54792

Actively Recruiting

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Research Team

I

Ihsan Ayyub Qazi, PhD

CONTACT

A

Ayesha Ali, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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