Finding Undiagnosed Chronic Respiratory Diseases in Adults with Other Long-Term Health Conditions in Brasil Using Questionnaires and Lung Function Tests

What this Trial Is About

Researchers are investigating ways to identify people in Brasil who may have undiagnosed chronic respiratory diseases CRDs like asthma and chronic obstructive pulmonary disease COPD. This study focuses on adults who already have other long-term health conditions such as heart disease, diabetes, or high blood pressure and attend primary health care centers in the cities of Sao Carlos and Sao Paulo. The goal is to evaluate simple questionnaires that can help detect these lung conditions early in people with other health problems. Participants will complete two questionnaires called COLA-6 and the Symptom-Based Questionnaire SBQ, which are quick and easy to use. Each person will also undergo lung function tests including spirometry before and after using a bronchodilator, as well as a fractional exhaled nitric oxide FeNO test to confirm lung health. Additional questionnaires related to asthma and chronic airway symptoms will be given to those with abnormal lung tests. The study will classify participants based on lung test results following recognized guidelines to identify different types of lung issues. All assessments are done during a single visit with a research team member. Participants will provide consent and undergo initial evaluations, questionnaires, and lung tests. The study will analyze how well the questionnaires identify abnormal lung function compared to spirometry results. Researchers will also collect information about participants health and lung conditions to better understand lung disease detection in people with other chronic illnesses. The study plans to recruit 859 individuals and will be completed by mid-2027.

Mitigating Chronic Respiratory Disease Through the Lens of Multi-Morbidity