Actively Recruiting
Mitigating PTSD-CUD After Sexual Assault
Led by University of Nevada, Las Vegas · Updated on 2026-01-16
68
Participants Needed
6
Research Sites
206 weeks
Total Duration
On this page
Sponsors
U
University of Nevada, Las Vegas
Lead Sponsor
U
University of North Carolina, Chapel Hill
Collaborating Sponsor
AI-Summary
What this Trial Is About
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD). The current proposal will test the acceptability, initial efficacy, and mechanisms underlying a novel digital therapeutic targeting risk for PTSD-CUD, which could address the critical need for PTSD-CUD prevention for the 100,000 women who annually present for emergency care after sexual assault. In this research context, the applicant will receive key training in multisite, emergency-care based randomized clinical trials (RCTs), advanced statistical analyses for RCTs and ecological momentary assessment data, biobehavioral mechanisms underlying PTSD-CUD prevention, and professional development, launching her independent research career focused on reducing the public health burden of PTSD-CUD among sexual assault survivors by leveraging digital therapeutics.
CONDITIONS
Official Title
Mitigating PTSD-CUD After Sexual Assault
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women sexual assault survivors presenting for emergency care less than 72 hours after assault at one of four emergency care sites
- English speakers
- 18 years of age or older
- Able to provide informed consent
- Have a smartphone with continuous service for more than one year
- Report using cannabis more than once per week on a substance use screener
- Report elevated anxiety sensitivity (greater than 17 on the Anxiety Sensitivity Index-3)
You will not qualify if you...
- Unable to provide informed consent due to serious injury, cognitive deficits, dementia, or being asleep at screening
- Prisoner
- Currently pregnant
- Living with the assailant and planning to continue living with them
- Admitted patient status
- No mailing address
- Previously enrolled in the study
- No sexual assault nurse examiner (SANE) examination
- Reporting current plan and intent for suicide or homicide
- Does not understand written and spoken English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Hennepin Assault Response Team
Minneapolis, Minnesota, United States, 55415
Not Yet Recruiting
2
University Medical Center
Las Vegas, Nevada, United States, 89102
Not Yet Recruiting
3
UNC Chapel Hill
Chapel Hill, North Carolina, United States, 27599
Not Yet Recruiting
4
Harbor Shelter
Smithfield, North Carolina, United States, 27577
Actively Recruiting
5
Tulsa Forensic Nursing
Tulsa, Oklahoma, United States, 74103
Not Yet Recruiting
6
SAFE Austin
Austin, Texas, United States, 74103
Actively Recruiting
Research Team
N
Nicole A Short, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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