Actively Recruiting
Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Led by Universitair Ziekenhuis Brussel · Updated on 2026-04-22
54
Participants Needed
1
Research Sites
23 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen. To have an idea of how well the mitochondria can produce energy, we can measure how much oxygen they use. The goal of this study is to: 1. To compare the oxygen use between people with long COVID and people who completely recovered after COVID-19, using three techniques that measure the oxygen use in blood cells, on the skin and in the muscle 2. To test how similar these three techniques are in measuring the oxygen used in the three different tissues Participants will: * Complete surveys, * Wear an activity tracker (7 days), * Undergo several non-invasive tests, and * Donate a blood sample The study will take place in UZ Brussel hospital and will take 2 study visits, approximately 7 days apart.
CONDITIONS
Official Title
Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older
- Diagnosis of long COVID based on the WHO definition
- Long COVID symptoms present for at least 6 months
- History of confirmed or documented SARS-CoV-2 infection
- Post-COVID-19 Functional Status Scale grade 2-4 during long COVID, with grade 0 before infection
- History of confirmed or documented SARS-CoV-2 infection with complete recovery and no long COVID symptoms
- Post-COVID-19 Functional Status Scale grade 0 before and after infection (for convalescent individuals)
You will not qualify if you...
- Pre-existing chronic diseases affecting functional status
- Treatment with metabolism altering drugs
- Consumption of more than 10 standard units of alcohol per week
- Inability to understand oral and written instructions in Dutch, French, or English
- Allergies to medical adhesive bandages
- Porphyria or other skin conditions worsened by sunlight
- Pre-existing chronic non-communicable diseases such as hypertension, chronic respiratory diseases, or diabetes (for convalescent individuals)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Laarbeeklaan 101
Jette, Brussels Capital, Belgium, 1090
Actively Recruiting
Research Team
B
Berenice G. Jimenez Garcia, Master of Science
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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