Open-labelled Study to Validate Home Use of a Health and Wellness Kit to Detect Urolithin A Levels in Dried Blood Spots After Mitopure Intake

What this Trial Is About

Researchers are conducting an open-labelled, virtual home-based study to evaluate the repeatability and failure or rejection rates of blood samples collected at home by participants. The study focuses on healthy adults aged 18 to 80 years and aims to measure levels of Urolithin A, a compound linked to healthy aging, in dried blood spots. The trial is sponsored by Amazentis SA and involves assessing the impact of dietary intake and supplementation on blood levels of Urolithin A. Participants will undergo a Mitopure challenge that includes consuming pomegranate juice followed by Mitopure supplementation, a proprietary Urolithin A dietary supplement provided as fruit-flavored sachets. Blood samples will be collected at home before and after the challenge to compare UA-Glucuronide levels. The study also involves completing health questionnaires to validate participants' health status related to the intervention. During the study, participants will collect dried blood spot samples at home over a 4-week period, which researchers will analyze for failure rates and sensitivity of the testing method. Participants will complete health questionnaires and monitor their intake of the study products. The research team aims to validate the home-based collection method and assess changes in Urolithin A levels, with all activities conducted in a virtual, participant-friendly setting.

The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots