Actively Recruiting
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Led by Medical College of Wisconsin · Updated on 2025-09-25
30
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.
CONDITIONS
Official Title
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 85 years of age
- Cortical or sub-cortical stroke at least 6 months ago with ongoing weakness on one side
- Able to give informed consent and follow two-step commands
- English speaking
You will not qualify if you...
- Unable to stand up from a chair without physical help from another person (assistive devices allowed)
- History of blood clots in the legs or any condition preventing thigh compression or causing transient ischemia (e.g., leg wounds)
- Severe COVID-19 symptoms lasting more than 6 months (e.g., hospitalization)
- Head trauma or concussion within past 6 months
- Other neurological disorders
- Peripheral vascular disease
- Heart attack or irregular heartbeat in the past year
- Resting blood pressure of systolic ≥180 mmHg or diastolic ≥100 mmHg
- Pregnant or breastfeeding
- Any other serious medical condition that may affect the study or safety as judged by the lead investigator
AI-Screening
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Trial Site Locations
Total: 1 location
1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
J
Jennifer Nguyen
CONTACT
A
Alicen Whitaker-Hilbig, DPT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
3
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