Actively Recruiting
MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
Led by University of Nebraska · Updated on 2026-02-24
60
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as intermittent claudication. We will be checking if MitoQ helps people with claudication walk better, be more active every day, feel better about their lives, and if it enhances the health of their leg muscles.
CONDITIONS
Official Title
MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a history of chronic claudication (leg pain when walking)
- Exercise-limiting claudication confirmed by medical history and observed walking test by a vascular surgeon
- Documented lower leg artery blockage shown by ankle/brachial index measurements or artery imaging
- Stable blood pressure, cholesterol, and diabetes treatments and risk factor control for at least 6 weeks
You will not qualify if you...
- Presence of rest pain or tissue loss due to peripheral artery disease (Fontaine stage III or IV)
- Recent acute lower leg ischemic event
- Walking ability mainly limited by other conditions such as joint, musculoskeletal, neurological, heart, or lung diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA Medical Center
Omaha, Nebraska, United States, 68105
Actively Recruiting
Research Team
H
Holly DeSpiegelaere, BSN RN CCRC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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