Actively Recruiting

Age: 18Years +
All Genders
NCT06633159

MitraClip in Patients With Heart Failure

Led by The League of Clinical Research, Russia · Updated on 2024-10-09

196

Participants Needed

1

Research Sites

85 weeks

Total Duration

On this page

Sponsors

T

The League of Clinical Research, Russia

Lead Sponsor

N

National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

Collaborating Sponsor

AI-Summary

What this Trial Is About

Multicenter observational study. The study does not involve any interventions in routine clinical practice, the choice of treatment method (including the type of medical device used and the method of surgical intervention) and the methods of examination and postoperative management of patients will not differ from the standard of care for patients requiring percutaneous transcatheter edge-to-edge mitral valve reconstruction by implantation of the MitraClip clip on the mitral valve leaflets, used in the daily medical practice of a medical institution. All medical devices under study (delivery device with the MitraClip clip on the mitral valve leaflets) are registered in the territory of the Russian Federation and are used in the conditions of routine medical practice. The study will include patients who have undergone surgical intervention to correct mitral regurgitation by percutaneous transcatheter implantation of the MitraClip G4 clip on the mitral valve leaflets. It is expected to include at least 196 patients (at least 98 prospective patients and at least 98 retrospective patients). The planned number of research centers is 11 outpatient clinics, presumably in 6 regions of the Russian Federation.

CONDITIONS

Official Title

MitraClip in Patients With Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients indicated for mitral regurgitation correction surgery using MitraClip G4 implantation
  • Age 18 years or older
  • Able to understand and voluntarily sign informed consent
  • Patients who have undergone mitral regurgitation correction with MitraClip G4 implantation (retrospective group)
  • Surgery performed on or after January 1, 2022 (retrospective group)
Not Eligible

You will not qualify if you...

  • Expected life expectancy less than 12 months
  • Other diseases limiting ability to attend study visits
  • Conditions limiting compliance with study requirements such as dementia, psychoneurological diseases, drug addiction, or alcoholism
  • Current participation in other clinical trials or prior participation in this trial
  • Lack of access to complete primary medical documentation for retrospective patients

AI-Screening

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Trial Site Locations

Total: 1 location

1

League of Clinical Research (LeagueCRR)

Moscow, Russia, 119590

Actively Recruiting

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Research Team

O

Oleg Melikhov, MD

CONTACT

S

Svetlana Elkonina

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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