Actively Recruiting
A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans with PTSD and Problematic Anger
Led by VA Office of Research and Development · Updated on 2025-10-20
150
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate a mobile health intervention for combat Veterans diagnosed with posttraumatic stress disorder (PTSD) who have difficulty controlling anger. Problematic anger in this group is linked to serious challenges such as social and work problems, family conflicts, aggression, and increased suicide risk. The study compares a new Mobile Anger Reduction Intervention (MARI), designed to reduce hostile interpretation bias, with a health education mobile app (HED) to see which better decreases anger and improves daily functioning. Participants will be randomly assigned to use either the MARI app or the HED app on their own smartphones for 4 weeks. The MARI app includes interpretation bias modification techniques, requiring at least five 10-minute sessions per week, plus tools like a nightly diary and progress tracking. The HED app provides videos on healthy habits and self-care, also used five times weekly. Both groups have equal usage expectations to compare effects fairly. Throughout the study, researchers will assess anger levels, hostile interpretation bias, social and occupational functioning, quality of life, and suicidal thoughts at the end of treatment, and at 3- and 6-month follow-ups. Participants' symptoms and app usage will be monitored, with outcomes measured to understand the impact of the mobile interventions. The total participation time includes the 4-week app use and subsequent follow-up assessments lasting up to 6 months after treatment starts.
CONDITIONS
Brief Title
Mobile Anger Reduction Intervention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veterans diagnosed with PTSD confirmed by chart review and a PTSD Checklist for DSM-5 (PCL-5) score of 33 or higher
- Reporting a score of 12 or higher on the 5-item Dimensions of Anger Reactions Scale
- No changes in type or dose of psychiatric medications for at least 3 months and no plans to change medications in the next 6 months
- Able to read materials at or above a 6th grade level
You will not qualify if you...
- Currently experiencing active psychosis or mania
- Having prominent suicidal or homicidal thoughts requiring immediate intervention
- Previous use of the Mobile Anger Reduction Intervention app in another research study
- Receiving or planning to receive other anger management or trauma-focused therapies for PTSD during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 4 weeks
Participants use a mobile application on their own smartphone to complete treatment sessions aimed at reducing anger and hostile interpretation bias.
Participants complete at least 5 sessions per week using the mobile app
Duration - 6 months
Participants are assessed for lasting effects on anger, hostile interpretation bias, psychosocial functioning, quality of life, and suicidal ideation.
Assessments at post-treatment, 3 months, and 6 months after treatment completion
Trial Site Locations
Total: 1 location
1
Durham VA Medical Center, Durham, NC
Durham, North Carolina, United States, 27705-3875
Actively Recruiting
Research Team
K
Kirsten H Dillon, PhD
A
Angela C Kirby, MS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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