Actively Recruiting

Phase Not Applicable
Age: 9Years - 17Years
All Genders
ID05390268

Mobile App-assisted Behavioral Treatment (MA-BT) in Children and Adolescents With a Chronic Tic Disorder Randomized Clinical Trial Evaluating Treatment Response and Satisfaction

Led by Aarhus University Hospital · Updated on 2025-02-21

60

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a mobile app-assisted behavioral treatment for children and adolescents aged 9 to 17 with chronic tic disorders, including Tourette syndrome. These neurodevelopmental disorders involve sudden, repetitive movements or vocalizations called tics, which can cause distress. The study aims to improve access to effective tic treatments that combine Habit Reversal Training (HRT) and Exposure Response Prevention (ERP) through a digital platform, making treatment more available and encouraging adherence, especially for those managed in primary care. Participants are randomly assigned to one of two groups: one receiving app-assisted training based on the "Niks til Tics" manual combining HRT and ERP over eight sessions plus a booster session, and the other receiving app-based psychoeducation about tics. The app releases new content session by session in the treatment group, while the education group accesses all app content from the first session. This randomized controlled trial compares the two approaches to assess the effectiveness of the app-assisted training. Throughout the study, participants undergo assessments including the Yale Global Tic Severity Scale (YGTSS) at multiple time points up to about two years after starting. Additional measures include scales for premonitory urges, beliefs about tics, and parent and child self-evaluations. The study also tracks treatment satisfaction and changes in tic intensity. The trial is sponsored by Aarhus University Hospital and aims to contribute new knowledge on digital interventions for tic disorders.

CONDITIONS

Brief Title

Mobile App-assisted Behavioral Treatment in Children and Adolescents With Tics

Who Can Participate

Age: 9Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a primary diagnosis of chronic motor or vocal tic disorder including Tourette syndrome according to WHO ICD-10 and DSM criteria
  • Have a total tic score higher than 13 on the Yale Global Tic Severity Scale, or above 9 if only motor or vocal tics are present
  • Are between 9 and 17 years old
Not Eligible

You will not qualify if you...

  • Have a psychotic disorder
  • Have primary severe depression
  • Have suicidal thoughts or attempts
  • Have a primary severe eating disorder
  • Have an IQ below 70
  • Have participated in tic training based on Habit Reversal Training or Exposure Response Prevention within the last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 23 weeks

Participants receive mobile app-assisted behavioral treatment or psychoeducation to manage tics through structured app sessions.

Visits at baseline, 5 weeks, 15 weeks, and 23 weeks

Follow-up

Duration - 52 to 73 weeks

Participants are monitored for long-term effects and treatment satisfaction up to nearly 2 years after treatment initiation.

1 visit between 75 and 96 weeks after baseline

Trial Site Locations

Total: 1 location

1

AarhusUH

Aarhus N, Risskov, Denmark, 8240

Actively Recruiting

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Research Team

J

judith nissen, phd

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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