Actively Recruiting
Mobile Applet for Weight Management in Obese Heart Failure Patients
Led by Heart Health Research Center · Updated on 2025-06-27
830
Participants Needed
26
Research Sites
134 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart failure. The main questions are: Does the use of a diet management APP and intelligent weight scale reduce 1-year all-cause mortality, heart failure hospitalization, and first heart failure hospital stay? Does the use of a diet management APP and intelligent weight scale improve the outcomes of assessment of heart failure frailty and quality of life for heart failure? Researchers will compare using the fully functional diet management app and intelligent weight scale to using the limitedly functional app and intelligent weight scale to see if the app works to improve heart failure conditions. Participants will: Use the diet management app at every meal and the intelligent weight scale every day for 12 months, and visit the clinic at 12 months for checkups.
CONDITIONS
Official Title
Mobile Applet for Weight Management in Obese Heart Failure Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Left ventricular ejection fraction (LVEF) 50% or less with New York Heart Association (NYHA) class II-III
- Body mass index (BMI) 26 kg/m² or higher, or male waist-to-hip ratio 0.9 or higher, female waist-to-hip ratio 0.85 or higher
- Ability to use a smartphone and comply with a diet management app during a 2-week run-in period
- History of heart failure hospitalization within the past 6 months
- Signed informed consent
You will not qualify if you...
- End-stage heart failure (2 or more hospitalizations for heart failure in the past 3 months, intolerance to guideline-directed medical therapy, or dependence on inotropic agents)
- Heart failure with reversible causes such as peripartum cardiomyopathy or fulminant myocarditis
- Moderate or severe anemia (hemoglobin less than 90 g/L)
- Renal insufficiency (eGFR less than 30 mL/min/1.73 m²) or ongoing dialysis
- Uncontrolled thyroid disease or end-stage liver failure
- Alcohol or substance abuse
- Current use of weight-loss medications or planned bariatric surgery
- Malignancy with expected survival less than 1 year
- Conditions likely to hinder protocol compliance (e.g., habitual reliance on food delivery or company cafeteria meals)
- Planned hospitalization during the trial period
- Participation in another interventional clinical study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 26 locations
1
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China, 100009
Actively Recruiting
2
Guangzhou Red Cross Hospital
Guangzhou, Guangdong, China
Actively Recruiting
3
Langfang People's Hospital
Langfang, Hebei, China
Actively Recruiting
4
Jixi City People's Hospital
Jixi, Heilongjiang, China
Actively Recruiting
5
Luoyang No.6 People's Hospital
Luoyang, Henan, China
Actively Recruiting
6
Ruyang County People's Hospital
Luoyang, Henan, China
Actively Recruiting
7
Ningling County People's Hospital
Shangqiu, Henan, China
Actively Recruiting
8
Yongcheng People's Hospital
Shangqiu, Henan, China
Actively Recruiting
9
Shangcheng County People's Hospital
Xinyang, Henan, China
Actively Recruiting
10
Henan Provincial Chest Hospital
Zhengzhou, Henan, China
Not Yet Recruiting
11
Tongliao People's Hospital
Tongliao, Inner Mongolia, China
Actively Recruiting
12
Xiu Yan Manchu Autonomous County Central People's Hospital
Anshan, Liaoning, China
Actively Recruiting
13
Tiemei General Hospital of Liaoning Health Industry Group
Diaobingshancun, Liaoning, China
Not Yet Recruiting
14
Shenyang Tenth Hospital
Shenyang, Liaoning, China
Actively Recruiting
15
Pingdu People's Hospital
Pingdu, Shandong, China
Actively Recruiting
16
Taian First Hospital
Taian, Shandong, China
Actively Recruiting
17
Weihai Central Hospital
Weihai, Shandong, China
Not Yet Recruiting
18
Qin Yuan County People's Hospital
Changzhi, Shanxi, China
Actively Recruiting
19
Xian Red Cross Hospital
Xian, Shanxi, China
Actively Recruiting
20
The First Affiliated Hospital of Xi'an Jiaotong University, Yulin Branch Hospital
Yulin, Shanxi, China
Actively Recruiting
21
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, The Xinjiang Uygur Autonomous Region, China
Actively Recruiting
22
Yuhuan Second People's Hospital
Taizhou, Zhejiang, China
Not Yet Recruiting
23
Beijing Chuiyangliu Hospital
Beijing, China
Not Yet Recruiting
24
Beijing Fangshan District First Hospital
Beijing, China
Actively Recruiting
25
Emergency General Hospital
Beijing, China
Not Yet Recruiting
26
Kaifeng Central Hospital
Kaifeng, China
Not Yet Recruiting
Research Team
Y
Yangyang Zhao
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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