Psychometric characteristics of the Multidimensional Scale of Perceived Social Support.
G D Zimet, S S Powell, G K Farley...
https://pubmed.ncbi.nlm.nih.gov/2280326/Actively Recruiting
Led by Fred Hutchinson Cancer Center · Updated on 2026-06-26
400
Participants Needed
4
Research Sites
17 weeks
Total Duration
Researchers are evaluating a new mobile health application called Planning Advance Care Together PACT to support people with advanced cancer in discussing and planning their care preferences with loved ones and doctors. This study focuses on patients with poor prognosis advanced cancer, including locally advanced or metastatic solid tumors, relapsed or refractory hematologic cancers, and those who have experienced disease progression after at least first-line systemic therapy. The goal is to enhance advance care planning by involving the patients social network. Participants are randomly assigned to one of two groups. One group uses the PACT mobile app for up to four weeks and receives a single check-in phone call during the study. The other group continues with standard care without any changes for the same period. After the intervention phase, all participants are followed up at three and six months to assess ongoing effects. During the study, participants complete questionnaires and provide feedback on usability, acceptability, and engagement with the app when applicable. Researchers track measures such as accrual rates, intervention completion, user satisfaction, time spent on the app, and changes in advance care planning conversations and documentation. Secondary outcomes include changes in treatment preferences, healthcare use, goal-concordant care, social support, and family functioning. The study lasts at least six months from intervention start to final follow-up.
CONDITIONS
Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
C
Claudia De Los Santos, B.S.
M
Megan Shen, PhD
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Fred Hutchinson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | PACT mobile app + telephone check‑in | Standard care |
|---|---|---|
| What the option is | A smartphone application (PACT) supported by telephone‑based check‑in to engage patients and support persons in advance care planning. | Best‑practice standard care advance care planning as delivered in current clinical services. |
| Role in the trial | Investigational intervention being tested in the study. | Active comparator reflecting usual advance care planning practice. |
| Primary use or purpose | To improve engagement in advance care planning through digital tools and telephone support. | To provide usual advance care planning without additional digital or check‑in support. |
| How it is delivered | Provision of a mobile app plus scheduled telephone‐based check‑in. | Usual care delivery without the app or structured telephone support. |
| Broader evidence or guideline context | Mobile apps and digital tools are among several formats studied to improve documentation and engagement in advance care planning, with evidence supporting various tools over usual care. | Advance care planning is recommended in oncology and serious illness care pathways and remains a core aspect of standard care. |
| Important risks | No specific safety risks are identified for mobile app‑based use; typical digital access considerations apply. | Risks are in line with routine clinical care; no added risks anticipated. |
| Important limitations | Requires internet access and ability to use a mobile device; may exclude those without digital access or ability. | Relies on usual clinical encounters to prompt ACP discussion, which may be infrequent or inconsistent. |
| Patient‑centric impact | May increase engagement and documentation of ACP behaviors compared with standard care. | Variable; without structured tools, ACP engagement and documentation may be lower. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 4 weeks
Participants are randomly assigned to use the PACT mobile app for up to four weeks with one check-in call, or to continue with standard care without changes.
One check-in call for app users
Duration - 6 months
Participants are followed up at three and six months after the intervention to assess outcomes and provide feedback.
Assessments at 3 and 6 months
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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Lead Sponsor
National Cancer Institute (NCI)
Collaborating Sponsor