Actively Recruiting
A Mobile Intervention to Reduce Pain and Improve Health-III for Older Adults with Knee or Hip Osteoarthritis
Led by Wake Forest University · Updated on 2026-02-20
200
Participants Needed
1
Research Sites
11 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University
Lead Sponsor
W
Wake Forest University Health Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying chronic pain in older adults, focusing on those with knee or hip osteoarthritis. This trial evaluates a mobile, remotely delivered behavioral intervention aimed at increasing physical activity and improving diet to reduce pain and enhance quality of life. The goal is to see if this approach can increase daily steps, reduce pain interference, lower body weight, and improve physical function over 6 months, with a follow-up maintenance phase lasting 12 months. Participants will be randomly assigned to one of two groups. The intervention group will join weekly group sessions with peers and receive individual coaching calls to encourage moving often throughout the day and adopting healthier eating habits to lose weight. They will use an activity monitor and a mobile app for feedback and goal-setting. The comparison group will receive an activity monitor and a wireless weight scale but no behavioral intervention. After 6 months, all participants enter a 12-month no-contact period to maintain their progress independently. During the study, participants will be assessed on daily steps, pain interference, body weight, physical function tests like the 30-second chair stand and gait speed at baseline, 6 months, and 18 months. Researchers will monitor changes in these areas to measure the intervention's effectiveness. Participants will attend virtual testing appointments and complete questionnaires, with the total study duration being 18 months including follow-up.
CONDITIONS
Brief Title
A Mobile Intervention to Reduce Pain and Improve Health-III
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 65 years or older
- Body mass index of 30-45 kg/m2, or above 45 kg/m2 with physician's approval
- No more than 5% change in body weight in the past 6 months
- Diagnosed with knee or hip osteoarthritis as confirmed by the Roux questionnaire
- Living independently
- Low physical activity levels (not regularly exercising more than 20 minutes per day on more than 2 days per week in past 3 months)
- No contraindications for safe exercise based on EASY screening
- Not currently using weight loss medications (diabetes medications allowed if weight stable)
- Approved for participation by medical director
- Willing to provide informed consent and complete all study procedures
You will not qualify if you...
- Living in skilled nursing, rehab, or assisted living facilities
- History of psychiatric treatment (other than depression or anxiety) in past year
- Current untreated or unstable depression or anxiety (PHQ-9 score over 15)
- Hospitalized for psychiatric reasons within past year
- History of mild cognitive impairment or dementia
- Cognitive impairment based on Modified Telephone Interview for Cognitive Status survey (score below 32)
- Hearing or vision issues preventing use of videoconferencing
- Severe arthritis or musculoskeletal disorders contraindicating safe walking
- Currently being treated for orthopedic fractures
- Currently using weight loss medications (except stable diabetes medications)
- Contraindications from EASY screening without physician approval
- Joint replacement or orthopedic surgery in past 6 months or planned within next 18 months
- Uncontrolled hypertension, recent severe heart disease, stroke, chronic respiratory disease (except asthma or COPD), oxygen use, neurological or hematological disease, cancer under treatment (except non-melanoma skin cancers), kidney failure requiring dialysis
- Katz ADL disability or heavy alcohol use (>14 drinks/week)
- Participation in other research studies with interventions
- Unable or unwilling to follow study protocol, including technology use and virtual appointments
- Unable or unwilling to attend three virtual testing sessions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (virtual)
Duration - 18 months
Participants receive a remote behavioral intervention or measurement-only monitoring to improve diet, activity behaviors, and health outcomes.
Weekly group sessions and individual coaching calls for MORPH participants; continuous use of activity monitor and wireless weight scale for all participants
Trial Site Locations
Total: 1 location
1
Wake Forest University
Winston-Salem, North Carolina, United States, 27109
Actively Recruiting
Research Team
D
Deja O Dobson, MS
J
Jason Fanning, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here