Actively Recruiting

Phase Not Applicable
Age: 50Years - 77Years
All Genders
ID07322367

A Pragmatic Randomized-Controlled Learning Health System Trial of mPATH-Lung A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

Led by Wake Forest University Health Sciences · Updated on 2026-03-25

27000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the real-world effectiveness of mPATH-Lung, a mobile patient health technology, in increasing lung cancer screening rates among diverse populations. This pragmatic, randomized controlled trial focuses on engaging racial/ethnic minorities and rural residents within an academic Learning Health System. The study aims to compare different outreach strategies and assess additional revenue from increased screenings, as well as potential over-screening effects. Participants will be randomly assigned to one of four groups: receiving a portal message followed by up to three reminder text messages, receiving text messages only with reminders, receiving a portal message only without reminders, or receiving usual care. Reminder messages vary depending on whether participants have upcoming appointments, with messages timed around appointments and program engagement. During the study, participants' lung cancer screening completion within 90 days will be tracked, along with eligibility, screening requests, and orders. Researchers will also evaluate revenue generated within 12 months and monitor potential over-screening. The involvement includes use of patient portals or cellphones for messaging, and data collection occurs through electronic health records and follow-up over time. The study enrollment is for patients aged 50 to 77 years with specific smoking histories and healthcare engagement requirements.

CONDITIONS

Brief Title

A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

Who Can Participate

Age: 50Years - 77Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 to 77 years
  • Smoked at least 20 pack years
  • Current smoker or quit smoking within the past 15 years
  • Established with a primary care provider within Atrium Health Wake Forest Baptist network
  • Have a patient portal account or cellphone number in the electronic health record
  • Have a North Carolina address listed in the electronic health record
Not Eligible

You will not qualify if you...

  • Need for a language interpreter other than English or Spanish
  • Prior history of lung cancer
  • Chest CT scan within the last 12 months
  • Meet HEDIS COL-E exclusion criteria due to significant comorbidities or frailty

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual)

Surveillance

Duration - Up to 90 days

Participants are engaged through different outreach strategies including portal messages and text message reminders to encourage lung cancer screening.

Participants receive messages and reminders digitally; no in-person visits required

Trial Site Locations

Total: 1 location

1

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

S

Study Coordinator

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

4

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