Mobile Video Directly Observed Therapy to Improve Immunosuppression Medication Adherence in Adolescent Heart Transplant Patients A Randomized Study to Enhance Medication Use and Patient Outcomes Using the eMocha DOT App

What this Trial Is About

Researchers are evaluating a mobile video directly observed therapy DOT intervention to improve medication adherence in adolescent heart transplant recipients. This population faces challenges with medication nonadherence, which can lead to late acute rejection, more hospitalizations, graft failure, and increased mortality. The study aims to promote better adherence and improve patient and graft outcomes using innovative technology. Participants are randomly assigned to one of two groups one group uses the eMocha DOT mobile app to track their medication doses asynchronously, while the other group continues with enhanced goal-setting as their standard care. The study follows these groups to compare how well the interventions support medication adherence over time. During the study, participants will be monitored for medication adherence using various measures such as medication level variability index and directly observed adherence. They will also complete questionnaires on patient activation, chronic illness care assessment, user satisfaction with the app, and quality of life. Outcomes like late acute rejection and hospitalizations will be tracked for six months after the intervention. The total participation involves assessments over 12 weeks and follow-up through six months post-intervention.

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients