Actively Recruiting
Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
Led by University of Florida · Updated on 2026-02-27
100
Participants Needed
4
Research Sites
134 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
E
emocha Mobile Health, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.
CONDITIONS
Official Title
Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 10 and 21 years
- Received a heart transplant and followed at participating pediatric heart transplant centers
- Speaks English or Spanish
- Owns a smartphone or can access the mobile app via other devices
- Willing to receive information through the app
- Has a medication level variability index (MLVI) score greater than 2.0 over the last year
You will not qualify if you...
- Cognitive impairments preventing the ability to provide informed assent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
University of Miami, Miller School of Medicine
Coral Gables, Florida, United States, 33146
Actively Recruiting
2
University of Florida
Gainesville, Florida, United States, 32610
Actively Recruiting
3
Joe DiMaggio Children's Hospital
Hollywood, Florida, United States, 33021
Actively Recruiting
4
FSU College of Medicine
Tallahassee, Florida, United States, 32306
Not Yet Recruiting
Research Team
D
Dipankar Gupta, MD
CONTACT
D
Dalia Lopez-Colon, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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