Actively Recruiting
Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling
Led by University of Delaware · Updated on 2023-08-24
72
Participants Needed
1
Research Sites
196 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Stroke is the third leading cause of death and the primary cause of long-term disability in the United States, affecting approximately 795,000 people each year. Hemiparesis, or unilateral weakness, is common after stroke and responsible for changes in muscle activation and movement patterns as well as declines in walking speed. It has been shown that increased walking speed directly corresponds to a higher quality of life in older adults and therefore, is often the goal of motor rehabilitation after stroke. However, there is no consensus on the best method for improving walking function after stroke and the results of post-stroke gait studies vary widely across sites and studies. Walking is one of the human's most important functions that serve survival, progress, and interaction. The force between the foot and the walking surface is very important. Although there have been many studies trying to understand this, there is a need for the development of a system that can advance research and provide new functionality. In this work, we will conduct a series of studies that attempt to analyze human gait and adaptations from different perspectives.
CONDITIONS
Official Title
Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged 18 to 80 years
- Proficient in English
- Physically fit for participation based on the Physical Readiness Questionnaire
- Resting heart rate between 60-100 beats per minute
- Resting blood pressure between 90/60 and 140/90 (Group A) or 90/60 and 160/90 (Group B)
- Weigh under 250 pounds
- For stroke survivors: single, unilateral, chronic stroke confirmed by MRI or CT scan
- Able to walk at a self-selected speed for at least 15 minutes without assistance
- Able to respond to screening questions, provide informed consent, and follow instructions
You will not qualify if you...
- Any neurological conditions besides stroke for stroke survivors or any neurological conditions for healthy subjects
- Inability to walk outside the home before the stroke
- Recent coronary artery bypass graft or myocardial infarction within 3 months
- Uncontrolled or untreated atrial fibrillation
- Severe or painful peripheral vascular disease
- Diagnosis of heart failure or unstable/untreated angina
- Expressive aphasia
- Musculoskeletal pain or conditions limiting walking (e.g., tendonitis, arthritis, osteoporosis, spinal stenosis, recent orthopedic surgery or fracture within 6 months)
- Inability to communicate with investigators due to cognitive impairment
- Severe respiratory problems such as COPD
- Unexplained dizziness
- Weight greater than 250 pounds
- Inability to ascend and descend 4 steps using handrails even with assistance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Delaware
Newark, Delaware, United States, 19716
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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