Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT05313815

Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer

Led by University Health Network, Toronto · Updated on 2024-06-18

100

Participants Needed

1

Research Sites

415 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single-arm phase II prospective trials that is recruiting 100 participants. The study population that is being investigated are patients with localized high-risk or node-positive prostate cancer. Participants will receive external beam radiotherapy as a moderately hypofractionated boost to the prostate with pelvic radiation therapy. Androgen deprivation therapy will be prescribed at the discretion of the treating physician as per standard of care.

CONDITIONS

Official Title

Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years
  • Able to provide informed consent
  • Histologic diagnosis of prostate adenocarcinoma
  • ECOG performance status 0-1
  • High-risk localized disease by NCCN criteria (>cT3, Grade group >4, or PSA >20 ng/mL) or clinical N1 disease
  • Clinical M0 by conventional imaging (CT and bone scan) and/or molecular imaging (PSMA-PET)
Not Eligible

You will not qualify if you...

  • Prior pelvic radiotherapy
  • Contraindications to radiotherapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Princess Margaret Cancer Center

Toronto, Ontario, Canada, M5G 2M9

Actively Recruiting

Loading map...

Research Team

R

Rachel Glicksman, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here