Actively Recruiting
Modified Deep Extubation vs. Standard Awake Extubation
Led by Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Updated on 2025-07-09
60
Participants Needed
1
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed study is to compare a modified DE technique, which is regularly used for low-risk patients by staff anesthesiologists at our institution, to a standard awake extubation. This modified deep extubation (mDE) occurs while the patient is still anaesthetized but at a lower dose of anaesthetic gas than previously described, and balanced with long acting opioids to attenuate the airway reaction. As previously stated, the literature shows that the risks of DE are equivalent to those of regular AE practice. Our hypothesis is that mDE will shorten the time from the end of the surgery (completion of last stitch) to the moment the patient is ready to leave the OR by at least 5 minutes when compared to standard AE practice.
CONDITIONS
Official Title
Modified Deep Extubation vs. Standard Awake Extubation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ASA physical status I to III
- Scheduled for laparoscopic surgery under general anesthesia
You will not qualify if you...
- Documented difficult airway during intubation or developed intraoperatively
- Full stomach
- Pregnant women
- Emergency surgery
- Body mass index (BMI) greater than 30
- Intraoperative bleeding leading to transfusion
- Use of remifentanil during extubation
- Requirement for prone position during surgery (e.g., spine surgery, anal fistulectomy, tumor resection of the back)
- Absolute requirement for awake or deep extubation
- Use of opioids for chronic pain
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Anesthesia Mount Sinai Hospital
Toronto, Ontario, Canada, M5G 1X5
Actively Recruiting
Research Team
N
naveed siddiqui, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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