Study of Modified Deep Lateral andor Medial Wall Orbital Decompression Surgery for Moderate-to-Severe Graves Ophthalmopathy

What this Trial Is About

Researchers are evaluating the effectiveness and safety of modified deep lateral wall decompression andor medial wall decompression surgeries for adults with moderate-to-severe Graves Ophthalmopathy. This study aims to develop a standard surgical approach to better treat this eye condition by comparing these decompression techniques. The trial is a prospective, interventional study sponsored by Sun Yat-sen University. The study involves a surgical procedure called modified deep lateral orbital wall decompression, which enhances the traditional outer wall decompression by including abrasion of the deep outer orbital wall. This allows for greater enlargement of the orbital cavity. Participants will receive this modified decompression surgery to assess its outcomes and possible complications. Participants will be monitored for up to 24 weeks after surgery, with assessments including best corrected visual acuity, measurements of eye protrusion Hertel value, visual field tests, visual evoked potentials, and clinical activity scores. During surgery, the volume of adipose tissue will also be evaluated. Regular follow-ups are required to track safety and effectiveness throughout the study period.

Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy