Postoperative pain management of the obese patient.
Stephan A Schug, Alexander Raymann
https://pubmed.ncbi.nlm.nih.gov/21516915Actively Recruiting
Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID06515691
Effectiveness of Ultrasound-Guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) for Postoperative Pain Control in Laparoscopic Sleeve Gastrectomy
Led by Istanbul Medipol University Hospital · Updated on 2025-12-24
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of the Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) for managing postoperative pain in patients undergoing Laparoscopic Sleeve Gastrectomy (LSG), a common bariatric surgery. The study focuses on whether M-TAPA can reduce opioid use within the first 24 hours after surgery, which is important since opioids can cause complications like breathing problems, nausea, and delayed recovery. This research is led by Istanbul Medipol University Hospital and aims to improve pain management and recovery in this patient group. The study compares two groups: one receiving the M-TAPA block along with standard postoperative pain care, and the other receiving only the standard pain management without the nerve block. The M-TAPA procedure involves ultrasound guidance to inject local anesthetic near the ribs to block specific nerve branches. Pain medications including ibuprofen, tramadol, and fentanyl via a patient-controlled system are used in both groups. The M-TAPA block is performed after surgery while the patient is still under general anesthesia. Participants will be monitored for opioid consumption and pain levels at multiple time points within 24 hours after surgery. Rescue pain medication use and any adverse events during this period will also be recorded. The study uses randomized, double-blind methods to compare outcomes. The total participation includes the surgery, treatment, and close monitoring for the first day after the operation to assess pain relief and medication needs.
CONDITIONS
Brief Title
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Who Can Participate
Age: 18Years - 65Years
All Genders
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- American Society of Anesthesiologists (ASA) classification II-III
- Scheduled for laparoscopic sleeve gastrectomy under general anesthesia
You will not qualify if you...
- History of bleeding diathesis
- Receiving anticoagulant treatment
- Allergies or sensitivity to drugs used in the study
- Infection at the puncture site
- History of alcohol or drug addiction
- Congestive heart failure
- Liver or kidney disease
- Declines to participate or does not accept the procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Day of surgery and 24 hours after surgery
Participants undergo laparoscopic sleeve gastrectomy under general anesthesia. For those in the experimental group, the M-TAPA block is performed after wound closure while still under anesthesia. All participants receive standard postoperative pain management, including medications and a patient-controlled analgesia system.
1 surgical visit and monitoring during the first 24 hours postoperatively
Trial Site Locations
Total: 1 location
1
Istanbul Medipol University Mega Hospital Complex
Istanbul, Bagcilar, Turkey (Türkiye)
Actively Recruiting
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Research Team
A
ayşe ince, assist pof
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Morbidity and effectiveness of laparoscopic sleeve gastrectomy, adjustable gastric band, and gastric bypass for morbid obesity.
Timothy D Jackson, Matthew M Hutter
https://pubmed.ncbi.nlm.nih.gov/22873044Opioid complications and side effects.
Ramsin Benyamin, Andrea M Trescot, Sukdeb Datta...
https://pubmed.ncbi.nlm.nih.gov/18443635Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) provides effective analgesia in abdominal surgery and is a choice for opioid sparing anesthesia.
Serkan Tulgar, Onur Selvi, David Terence Thomas...
https://pubmed.ncbi.nlm.nih.gov/30639940Clinical Experience for Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Five Patients. Dermatomal Evaluation and Application of Different Volumes: A Case Series and Review of Literature.
Bahadır Çiftçi, Hande Güngör, Selçuk Alver...
https://pubmed.ncbi.nlm.nih.gov/37587679Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) provides a sufficient postoperative analgesia for laparoscopic sleeve gastrectomy.
Katsuhiro Aikawa, Nobuhiro Tanaka, Yuji Morimoto
https://pubmed.ncbi.nlm.nih.gov/31212124