Actively Recruiting
Modulating Exercise Dosage to Improve Concussion Recovery
Led by University of Colorado, Denver · Updated on 2026-05-06
216
Participants Needed
3
Research Sites
234 weeks
Total Duration
On this page
Sponsors
U
University of Colorado, Denver
Lead Sponsor
B
Boston Children's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects, how exercise can alter concussion-related pathophysiology, and whether exercise can prevent the development of secondary sequelae. Our objective is to examine if a high dose exercise program (higher volume than currently prescribed at an individualized, safe intensity level) initiated within 14 days of concussion results in faster symptom resolution, altered physiological function, or reduced secondary sequalae. Findings from this research will lead to more rigorous and precise rehabilitation guidelines and improved understanding about how exercise affects neurophysiological function among adolescents with concussion.
CONDITIONS
Official Title
Modulating Exercise Dosage to Improve Concussion Recovery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 13-18 years of age
- Post-Concussion Symptom Scale (PCSS) score >10 to ensure participants are not recovered by enrollment
- Concussion diagnosis by a sports medicine physician
You will not qualify if you...
- Pre-existing neurological disorders
- Exercise contraindications
- Concussion <6 months before enrollment (excluding the current injury)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University of Colorado Denver
Aurora, Colorado, United States, 80045
Actively Recruiting
2
Boston Children's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
3
Spaulding Rehabilitation Hospital
Cambridge, Massachusetts, United States, 02138
Actively Recruiting
Research Team
D
David R Howell, PhD
CONTACT
K
Kelsie Richardson, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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