Actively Recruiting
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Led by Rutgers, The State University of New Jersey · Updated on 2025-11-17
60
Participants Needed
1
Research Sites
179 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is believed to index the sensitivity of the parahippocampal cortex to spatial context. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in virtual navigation tasks, and if so, whether it would affect the spatial encoding of rewards and subsequent choices during task performance.
CONDITIONS
Official Title
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between the ages of 18 and 55 years old.
- Not received substance abuse treatment within the previous 30 days.
- Be in stable mental and physical health.
- If female, test non-pregnant.
- No evidence of focal or diffuse brain lesion on MRI.
- Be willing to provide informed consent.
- Be able to comply with protocol requirements and likely to complete all study procedures.
You will not qualify if you...
- Contraindication to MRI such as metal in the skull, orbits or intracranial cavity, or claustrophobia.
- Contraindication to rTMS including history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for more than 15 minutes.
- Implanted electronic device, metal in the head, or pregnancy.
- History of autoimmune, endocrine, viral, or vascular disorders affecting the brain.
- History or MRI evidence of neurological disorder causing brain lesions or significant physical impairment.
- Lifetime history of mental disorders such as Bipolar Affective Disorder, Schizophrenia, Post-traumatic Stress Disorder, Dementia, or Major Depression.
- Use of uninterruptable central nervous system medication.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Rutgers University - Newark
Newark, New Jersey, United States, 07102
Actively Recruiting
Research Team
T
Travis E Baker, PhD
CONTACT
M
Malte Gueth
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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