Actively Recruiting
Modulating Inhibitory Control Networks in Gambling Disorder With Theta Burst Stimulation
Led by CNS Onlus · Updated on 2018-09-13
40
Participants Needed
1
Research Sites
80 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this project the investigators propose a randomized double-blind placebo-controlled design in which 40 patients with GD will receive active or sham cTBS to the pre-SMA for 2 weeks. The investigators will combine TMS, multimodal structural and functional MRI and behavioral measures in order to identify circuit-level mechanisms of action and therapeutic targets (connectivity changes that explain clinical improvement) and assess the efficacy of TMS in modulating inhibitory control and symptom severity in this population.
CONDITIONS
Official Title
Modulating Inhibitory Control Networks in Gambling Disorder With Theta Burst Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Gambling Disorder according to DSM-5
- Age between 18 and 65 years
You will not qualify if you...
- Any current psychiatric disorder except nicotine addiction
- Lifetime diagnosis of schizophrenia, psychotic syndromes, substance dependence or abuse, bipolar I or II disorder, or mental disorder due to a medical condition
- Serious risk of suicide
- Illness duration less than two years
- Hospitalization within the last 6 months
- Inability to receive TMS due to metal implants or personal/family history of seizures
- Any major medical illness
- Pregnancy or nursing an infant
- Inability or refusal to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CNSOnlus, Institute of Neuroscience
Florence, Italy, 50100
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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