Actively Recruiting

Age: 0 - 18Years
All Genders
NCT02775643

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

Led by St. Jude Children's Research Hospital · Updated on 2025-11-10

500

Participants Needed

1

Research Sites

1304 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is an observational, non-therapeutic study to collect clinical and molecular information of pediatric patients with childhood melanocytic lesions. PRIMARY OBJECTIVE: To perform a comprehensive molecular analysis of samples either from paraffin embedded and/or frozen tissue from patients with pediatric melanocytic lesions (including melanoma, spitzoid melanoma, congenital melanoma, melanoma arising in giant nevi). SECONDARY OBJECTIVE: To collect minimal information on patients treated with adjuvant or systemic therapies according to National Comprehensive Cancer Network (NCCN) guidelines.

CONDITIONS

Official Title

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant has a suspected or confirmed melanocytic lesion, including conventional melanoma, spitzoid melanoma/atypical Spitz tumor, congenital melanoma, melanoma arising in a giant congenital nevus, or melanocytic lesions with uncertain biological behavior
  • Participant was younger than 19 years old at diagnosis
  • Tissue from the tumor is available for biological studies
  • Participant has been or will be enrolled in the TBANK protocol at St. Jude Children's Research Hospital before any research testing
Not Eligible

You will not qualify if you...

  • Diagnosis of ocular melanoma
  • Inability or unwillingness of participant or legal guardian to give consent
  • Histologic diagnosis other than the melanocytic lesions listed in inclusion

AI-Screening

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Trial Site Locations

Total: 1 location

1

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105

Actively Recruiting

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Research Team

A

Alberto Pappo, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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