Actively Recruiting

Age: 0 - 45Years
All Genders
NCT02168088

Molecular Autopsy Study

Led by Scripps Translational Science Institute · Updated on 2025-01-16

100

Participants Needed

1

Research Sites

834 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.

CONDITIONS

Official Title

Molecular Autopsy Study

Who Can Participate

Age: 0 - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Index case age between birth and 45 years
  • Clinical presentation of sudden or unexplained death believed to be cardiac in nature or secondary to a massive unprovoked pulmonary embolism with no prior diagnosis of prothrombotic disease
Not Eligible

You will not qualify if you...

  • Premature death secondary to murder, suicide, or external causal event
  • Premature death thought secondary to known chronic comorbid medical condition
  • Premature death thought secondary to end-organ failure (kidney, liver, lung) other than heart
  • Previously diagnosed with hypertrophic cardiomyopathy (HCM)
  • Prior myocardial infarction regardless of stenting or bypass
  • Prior cerebrovascular accident (stroke or transient ischemic attack)
  • History of open heart surgery for any reason
  • History of severe, untreated hypertensive heart disease
  • History of illicit drug use
  • History of heavy alcohol abuse
  • History of severe pulmonary disease
  • History of morbid obesity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Scripps Translational Science Institute

La Jolla, California, United States, 92037

Actively Recruiting

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Research Team

S

Sarah Topol, RN

CONTACT

E

Emily Spencer, Phd

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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