Actively Recruiting
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Led by Meyer Children's Hospital IRCCS · Updated on 2024-03-12
340
Participants Needed
3
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through centralization of biological samples at reference laboratories outside the Tuscany Region. In order to preserve the wealth of clinical and biological data and use it for the benefit of present and future patients treated at the CROP centers, it is useful to evaluate the feasibility of centralization and molecular typing of mutations present in tumor tissue at the IRCCS AOU Meyer Oncohematology Laboratories and subsequently the analysis of clinical data from patients with diseases not under study to lay the foundations of a translational database that can then be associated with a biobank in the future. This will enable a targeted contribution to pediatric oncohematology research, investing in possible targeted therapies with those patient subgroups that benefit from personalized disease assessment in mind. The goal of the project is to improve the regional infrastructure dedicated to organized data collection and management of biological samples in adequate time resulting in better and more comprehensive data collection.
CONDITIONS
Official Title
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnostic suspicion of oncologic, hematologic or onco-immunologic disease
- Suspected recurrence of oncological, onco-hematological, hematological or onco-immunological disease
- Availability of biological material
- Signature of informed consent
- Age between 0 and 30 years
You will not qualify if you...
- Failure to sign the consent
- Insufficiency of biological material for analysis
- Patients with HIV, HCV and HBV seropositivity (HBSAg) due to biohazard and bias related to patients' immunological status that could influence gene expression and tumor behavior.
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Meyer Children's Hospital IRCCS
Florence, Italy
Actively Recruiting
2
Azienda Ospedaliero-Universitaria Pisana
Pisa, Italy
Actively Recruiting
3
Azienda Ospedaliero-Universitaria Senese
Siena, Italy
Actively Recruiting
Research Team
M
Marinella Veltroni
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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