Actively Recruiting
Molecular Landscape of Microvascular Inflammation in Kidney Allografts
Led by Paris Translational Research Center for Organ Transplantation · Updated on 2025-05-31
600
Participants Needed
3
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Microvascular inflammation in kidney allografts has been widely reappraised in the recent update of Banff classification. There is a critical need to better understand the pathophysiological mechanisms associated with the various phenotypes of microvascular inflammation that are observed in kidney transplants, particularly in order to develop targeted therapeutic approaches.
CONDITIONS
Official Title
Molecular Landscape of Microvascular Inflammation in Kidney Allografts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult kidney transplant recipients
- At least one kidney transplant biopsy performed and assessed according to the international Banff 2022 classification
- Biopsies may have lesions of microvascular inflammation or none
You will not qualify if you...
- Biopsy inadequate according to the Banff classification
- Missing data for Banff lesion scores, donor-specific antibody status, or C4d staining
- Biopsies showing histological signs of ischemia-reperfusion injury
- Combined transplantation or kidney transplantation after a non-kidney solid organ transplant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Kidney Transplant Department, Saint-Louis Hospital, Assistance Publique - Hôpitaux de Paris
Paris, France, 75010
Actively Recruiting
2
Kidney Transplant Department, Necker Hospital, Assistance Publique - Hôpitaux de Paris
Paris, France, 75015
Actively Recruiting
3
Bichat Hospital, Assistance Publique - Hôpitaux de Paris
Paris, France, 75018
Actively Recruiting
Research Team
A
Alexandre Loupy, MD PhD
CONTACT
C
Catherine Tritscher
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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