Actively Recruiting
The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]
Led by Samsung Medical Center · Updated on 2026-04-28
797
Participants Needed
6
Research Sites
657 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This protocol is a molecular screening protocol only. No drug intervention study will be included in this protocol. Based on the molecular profiling, patients may be eligible for drug intervention study of SUKSES trial. This procedure can be performed during or after the first-line treatment. DNA will be extracted from the archived or fresh tissue and blood. NGS-based cancer panel and Nanostring CNV will be tested with DNA from tissue and/or blood. Immunohistochemistry and FISH will be done by pathologists using archived or fresh tissue. Tumor tissues (fresh or archival) will be analyzed using NGS-based cancer panel, nanostring CNV, immunohistochemistry and/or FISH. Specific methods of each molecular tests will be defined with standard laboratory manual developed by pathologists.
CONDITIONS
Official Title
The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide fully informed consent before study procedures
- Be 20 years of age or older
- Have histologically or cytologically confirmed small cell lung cancer
- Have an ECOG performance status of 0 to 2
- Have been treated or are being treated with platinum-based chemotherapy as first-line treatment
- Have available archival tissue for molecular analysis or agree to biopsy for such analysis
You will not qualify if you...
- Have had more than two prior chemotherapy regimens for small cell lung cancer
- Be pregnant or nursing (women of reproductive potential must agree to use effective contraception)
- Have a second primary cancer, except adequately treated non-melanoma skin cancer, curatively treated in-situ cervical cancer, or other solid tumors treated with no evidence of disease for 2 years or more
AI-Screening
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Trial Site Locations
Total: 6 locations
1
Gachon University Gil Medical Center
Incheon, South Korea
Completed
2
Chungbuk University Hospital
Jungbuk, South Korea
Completed
3
Seoul National University Bundang Hospital
Seongnam, South Korea
Completed
4
Samsung Medical Center
Seoul, South Korea, 135-710
Actively Recruiting
5
VHS Medical Center
Seoul, South Korea
Completed
6
Ulsan University Hospital
Ulsan, South Korea
Completed
Research Team
S
Se-Hoon Lee, MD,Ph.D.
CONTACT
S
Seoha Kim
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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