Actively Recruiting
MOLyF : Bone Marrow and Follicular Lymphoma
Led by Rennes University Hospital · Updated on 2024-12-10
200
Participants Needed
1
Research Sites
512 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective single-center study designed to assess potential differences in cell composition between bone marrows of patients with follicular lymphoma and those from control subjects. Follicular lymphoma is the most common indolent lymphoma. It is characterised by systematic relapses and bone marrow dissemination in 70% of patients at the time of diagnosis. Although relapses are thought to be related to refractory tumour cells nested in a supportive microenvironment in the bone marrow, the mechanisms involved are poorly understood. To study the specificities of the bone marrow of patients with follicular lymphoma, It is necessary to compare them with control samples. This study takes advantage of surgeries involving sternotomies to recover lost bone marrow and establish a bone marrow bank of patients without hematological disease. This bank will be used to set up control cohorts for other clinical trials involving patients with follicular lymphoma.
CONDITIONS
Official Title
MOLyF : Bone Marrow and Follicular Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Hospitalized in the thoracic, cardiac, or vascular surgery department for surgery involving a sternotomy
- Provided free, informed, written consent
- Covered by a health insurance scheme
You will not qualify if you...
- History of hematological malignancy or abnormal blood counts
- Currently receiving immunomodulating treatments such as immunosuppressants, corticosteroids, or antineoplastic drugs
- Individuals protected under French Public Health Code articles L. 1121-5 to L. 1121-8 and L. 1122-1-2, including minors and protected adults
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHU Rennes
Rennes, France, 35009
Actively Recruiting
Research Team
J
Juliette Ferrant, MD
CONTACT
A
Alexandra Guerrier
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here