Actively Recruiting

Phase Not Applicable
Age: 14Years - 17Years
All Genders
Healthy Volunteers
NCT06369623

Monetary Incentive Delay Task for Probing Reward-related Neural Processes

Led by Stony Brook University · Updated on 2025-05-15

300

Participants Needed

1

Research Sites

242 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

150 males and 150 females ages 14-17 years-old will be enrolled in an observational, longitudinal study. There are three planned in-person visits: a baseline assessment, an 18-month follow-up, and a 36-month follow-up. The in-person visits will include assessment of substance use and other individual differences (e.g., reward function, psychiatric history), neuromelanin-sensitive MRI, as well as functional brain activation collected while the participant is at rest (resting-state fMRI) and while the participant completes a Monetary Incentive Delay task. Subjects will also be asked to complete past 90-day substance use assessments remotely every 90 days for 36 months.

CONDITIONS

Official Title

Monetary Incentive Delay Task for Probing Reward-related Neural Processes

Who Can Participate

Age: 14Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females ages 14-17 years old
  • Able to speak English to provide assent and complete interviews
  • Capacity to give assent
  • Parents willing and able to provide permission/consent
Not Eligible

You will not qualify if you...

  • Current use (within 6 months) of medication that may affect brain function
  • History of severe medical or neurological illness including stroke or seizure
  • History of head trauma with loss of consciousness
  • Presence of metal in the body
  • Pregnancy or breastfeeding
  • Recent drug or alcohol use confirmed by urine or breath tests
  • Lifetime use of psychotropic or dopamine-influencing medication, except some youth with history of stimulant or antipsychotic medication included for comparison

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stony Brook Medicine

Stony Brook, New York, United States, 11794

Actively Recruiting

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Research Team

G

Greg Perlman, PhD

CONTACT

L

Lu-Ann Kozlowski, BSN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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