Actively Recruiting
Monitoring Changes in Blood Circulating Metabolites Using Minimally Invasive Techniques
Led by Örebro University, Sweden · Updated on 2026-04-14
35
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates short-term intra- and inter-individual variability in human blood metabolism under real-life conditions. Using minimally invasive finger-prick blood sampling, dietary records, and wearable devices, we will longitudinally monitor blood-circulating metabolites and glucose levels in healthy individuals over a four-week period without dietary or lifestyle intervention. The study focuses on metabolic transitions between pre- and postprandial states during habitual daily activities and routine meals. Mass spectrometry-based metabolomics will be used to characterize metabolite profiles and their associations with diet, physical activity, sleep, and stress. In parallel, the study evaluates the feasibility of microsampling approaches, wearable-derived physiological data, and isotope-labelled standards for robust and cost-effective metabolite quantification. The results will inform the design of larger longitudinal studies using minimally invasive blood sampling in non-controlled settings.
CONDITIONS
Official Title
Monitoring Changes in Blood Circulating Metabolites Using Minimally Invasive Techniques
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Body Mass Index (BMI) between 18.5 and 29.9 kg/m2
- Stable weight during the previous 3 months (self-reported)
- Willing to maintain usual physical activity and eating habits during the study
You will not qualify if you...
- Having acute or chronic diseases, inflammatory or functional gastrointestinal disorders, or any disease that affects daily activities
- Regular use of medications or supplements that might affect study results
- History of eating disorders
- Use of antibiotics within 3 months before the study start
- Actively trying to lose weight
- Smoking
- Drinking more than nine standard alcoholic drinks per week or more than three drinks per occasion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
School of Medical Sciences
Örebro, Sweden, 70281
Actively Recruiting
Research Team
A
Anh Hoang Nguyen, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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