Actively Recruiting

Age: 18Years +
All Genders
NCT07212439

Monitoring Coughs for the Early Detection of Worsening COPD

Led by Clinica Universidad de Navarra, Universidad de Navarra · Updated on 2026-01-02

50

Participants Needed

3

Research Sites

43 weeks

Total Duration

On this page

Sponsors

C

Clinica Universidad de Navarra, Universidad de Navarra

Lead Sponsor

H

Hyfe Inc

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is for adults with COPD. Flare-ups of COPD, also known as exacerbations, can be serious and lead to hospital stays. The purpose of this research is to see if continuously and automatically monitoring a person's coughs can help predict these flare-ups early, before they become severe. Participants will use the Hyfe cough monitoring system, which includes a watch-like device worn on the wrist and a smartphone application. The system privately counts the number of coughs without recording any audio. Participants will also answer a short, weekly questionnaire about their COPD symptoms. This is an observational study, which means it will not change the regular medical care a participant receives. The participants and their care providers will not see the cough counts. The doctor will continue to manage their COPD as usual.

CONDITIONS

Official Title

Monitoring Coughs for the Early Detection of Worsening COPD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be 18 years of age or older.
  • Must have an existing diagnosis of COPD.
  • For the inpatient cohort, participants must be currently assessed as having a moderate/severe exacerbation.
  • For the outpatient cohort, participants must have had at least one exacerbation of any severity in the last 12 months.
  • For the outpatient cohort, at least one month must have passed since the last exacerbation.
Not Eligible

You will not qualify if you...

  • Individuals who are unable to provide informed consent.
  • Individuals who are unable to adhere to study procedures.
  • For the inpatient cohort, individuals requiring invasive or non-invasive ventilation.
  • Individuals who live with a person who has a chronic cough.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Clinica San Miguel

Pamplona, Navarre, Spain, 31006

Actively Recruiting

2

Clínica Universidad de Navarra, Universidad de Navarra

Pamplona, Navarre, Spain, 31008

Actively Recruiting

3

Servicio Navarro de Salud

Pamplona, Navarre, Spain, 31008

Actively Recruiting

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Research Team

C

Carlos J. Chaccour, MD, PhD

CONTACT

F

Fhabián S. Carrión-Nessi, MD, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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