Actively Recruiting

Age: 1Year - 19Years
All Genders
ID07245654

Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients: a Prospective Observational Study

Led by Brno University Hospital · Updated on 2025-11-24

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the use of a device called Conox to monitor the depth of anesthesia and pain relief during the induction of general anesthesia in children aged 1 to 19 years undergoing elective surgery. The study aims to evaluate whether anesthesia and analgesia levels during airway management are adequate, as insufficient levels may lead to increased episodes of wakefulness or postoperative delirium. This observational study is conducted under routine anesthesia care to improve safety during surgery. Before anesthesia begins, electrodes from the Conox device are placed on the child's forehead to continuously monitor anesthesia depth and pain levels. The anesthesiologist manages anesthesia induction either through intravenous or inhalation methods while airway management techniques such as laryngeal mask or intubation are performed. The study records opioid use, airway management methods, and any episodes of burst suppression during surgery. After surgery, the team observes the child for any signs of postoperative delirium in the recovery room. Participants will be monitored throughout the perioperative period without any additional interventions beyond standard care. The study collects data on anesthesia depth using the qCON index, clinical responses during airway management, and postoperative outcomes. Researchers will analyze factors contributing to anesthesia adequacy and postoperative complications. The total involvement covers the surgical procedure and immediate recovery phase, ensuring detailed observation of anesthesia effects in pediatric patients.

CONDITIONS

Brief Title

Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients

Who Can Participate

Age: 1Year - 19Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric patients aged 1 to 19 years scheduled for surgery under general anesthesia with airway management (laryngeal mask, orotracheal intubation, nasotracheal intubation)
  • CONOX monitoring available during the procedure
  • Elective surgery with expected duration longer than 30 minutes
Not Eligible

You will not qualify if you...

  • Age outside 1 to 19 years range
  • Use of ketamine during anesthesia care (premedication, analgesic, anesthetic)
  • Expected surgery duration less than 30 minutes
  • CONOX monitoring not available during procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Day of surgery

Before anesthesia induction, electrodes for monitoring are applied and baseline monitoring of anesthesia depth and analgesia is initiated.

1 visit (in-person during surgery)

Monitoring

Duration - During surgery and immediate postoperative period

Participants are observed during anesthesia induction, airway management, and postoperative recovery to monitor anesthesia depth, analgesia levels, opioid use, and postoperative delirium.

Continuous monitoring during surgery and recovery room stay

Trial Site Locations

Total: 1 location

1

University Hospital Brno

Brno, Czechia, 62500

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Research Team

T

Tereza Bonischova, MD

H

Hana Harazim, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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