Actively Recruiting

Age: 18Years +
All Genders
NCT05649865

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

Led by Region Skane · Updated on 2023-06-08

150

Participants Needed

1

Research Sites

259 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine the value of circulating tumour HPV DNA (human papilloma virus DNA found in the blood) at diagnosis, during treatment, and in the follow-up of patients diagnosed and treated for throat cancer caused by HPV. The main question to answer is if the presence of HPV DNA in the blood one month after the treatment is useful in detecting remaining tumour or relapse within two years after treatment. The participants will be asked to provide blood tests: 1. before treatment 2. weekly during the treatment 3. on all scheduled follow-up appointments 4. on all unplanned appointments where a relapse is suspected

CONDITIONS

Official Title

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients must have an HPV-positive primary throat tumour confirmed by biopsy.
  • Patients must be older than 18 years.
  • Patients must be able to give informed consent.
  • Patients must be planned for treatment with curative intent.
Not Eligible

You will not qualify if you...

  • Patients with a short expected lifespan.
  • Patients with psychiatric or addictive disorders that may affect study participation.
  • Patients with other medical conditions that could impair compliance, as determined by the investigator.

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Dept. of ORL-HNS

Lund, Skåne County, Sweden, 22185

Actively Recruiting

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Research Team

J

Johanna Sjövall, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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