Actively Recruiting

Age: 18Years +
All Genders
NCT01311258

Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome

Led by University of Rochester · Updated on 2025-09-17

400

Participants Needed

1

Research Sites

1200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is being performed to develop assays to determine the impact of the therapy patients receive for treatment of AML or MDS and to determine if these tests can identify those patients who are at a greater risk for having their disease relapse.

CONDITIONS

Official Title

Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Being evaluated for diagnosis and/or treatment of Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome with more than 10 percent blasts in bone marrow
  • No cytotoxic therapy for AML or High Grade MDS in past 3 months except hydroxyurea or Revlimid
  • No prior allogeneic peripheral blood or bone marrow stem cell transplant for the disease
  • Able to sign informed consent before any specimen or clinical data collection
  • At least 18 years of age
  • No serious medical or psychiatric illness limiting therapy or consent ability
  • Informed of investigational nature and provided written informed consent as per guidelines
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Limited decision-making capacity
  • Received cytotoxic therapy other than hydroxyurea or Revlimid within past 3 months
  • Diagnosed with chronic myelogenous leukemia in blast crisis, Acute Promyelocytic Leukemia, or Bi-lineage leukemia
  • Previously undergone allogeneic peripheral blood stem cell transplant
  • Active malignancy other than AML or MDS or history of treatment for other malignancy within past 2 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Rochester Medical Center

Rochester, New York, United States, 14642

Actively Recruiting

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Research Team

M

Michael W Becker, MD

CONTACT

J

Jamie Littleton, MSN,RN,CCRC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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