Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06601842

Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Led by National Taiwan University Hospital · Updated on 2024-12-16

50

Participants Needed

1

Research Sites

103 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis. Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.

CONDITIONS

Official Title

Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-traumatic cardiac arrest
  • Admitted to intensive care unit (ICU)
  • Glasgow Coma Scale motor score of 5 or less
  • Medium-risk group according to TIMECARD severity score
Not Eligible

You will not qualify if you...

  • Traumatic cardiac arrest
  • Pregnancy
  • Intracranial hemorrhage
  • Coagulopathy
  • Use of anti-platelet or anti-coagulation medications
  • Terminal illness
  • Pre-arrest Cerebral Performance Category (CPC) score of 3 or higher
  • Gray-White Matter Ratio (GWR) less than 1.2 on CT or severe hypoxic ischemic encephalopathy
  • Central nervous system (CNS) infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

D

Dean-An Ling, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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